Küchle H J
Klin Monbl Augenheilkd. 1977 Sep;171(3):395-406.
After discussing basic therapeutic principles for the treatment of acute arterial occlusions of the retina and N. opticus (fibrinolysis, anticoagulation, corticoids, vasoactive drugs) the problems in employment of vasodilating drugs and the necessity of concomitant administration of strophanthine or digitalisglycosides are outlined. Results obtained after the administration of 3,7-Dimethyl-1-(5-oxo-hexyl)-xanthine (Pentoxifylline, Trental) in the treatment of 49 cases suffering from occlusion of the retinal vessels and 23 cases with vascular occlusion in the N. opticus are reported and commented with a view to the bad prognosis of these serious disorders, 55% of the patients showing definite improvement of visual acuity. Therapeutic guidelines resulting from these experiences are presented.
在讨论了视网膜和视神经急性动脉闭塞的基本治疗原则（纤维蛋白溶解、抗凝、皮质类固醇、血管活性药物）后，概述了血管扩张药物的使用问题以及同时给予毒毛旋花子苷或洋地黄糖苷的必要性。报告了3,7-二甲基-1-(5-氧代己基) - 黄嘌呤（己酮可可碱，曲克芦丁）治疗49例视网膜血管闭塞和23例视神经血管闭塞患者的结果，并鉴于这些严重疾病的不良预后进行了评论，55%的患者视力有明显改善。还介绍了基于这些经验得出的治疗指南。
