Kellner H
MMW Munch Med Wochenschr. 1976 Oct 22;118(43):1399-1402.
For the objective determination of its efficacy, Trental 400 was examined against placebo in a double blind trial in 40 patients with chronic peripheral circulatory disorders and concomitant symptoms of cerebro-vascular insufficiency typical of age. Treatment lasted 7 to 8 weeks with a dosage of 1 tablet 3 times a day. Trental 400 was significantly more effective than placebo in the treatment of peripheral and cerebral disorders. The preparation was well tolerated, subjectively and objectively.
为客观确定其疗效，在一项双盲试验中，对40例患有慢性外周循环障碍及伴有典型老年脑血管供血不足症状的患者，将曲克芦丁400与安慰剂进行了对比研究。治疗持续7至8周，剂量为每日3次，每次1片。在治疗外周和脑部疾病方面，曲克芦丁400比安慰剂显著更有效。该制剂在主观和客观上耐受性良好。
