Wilson C A, Choromokos E A, Sheppard R
Department of Ophthalmology, University of Cincinnati College of Medicine, OH.
Arch Ophthalmol. 1988 Jun;106(6):796-800. doi: 10.1001/archopht.1988.01060130866042.
Four cases of suspected cerebral vasculitis have been described in association with acute posterior multifocal placoid pigment epitheliopathy, but none was confirmed histopathologically. We describe a patient who developed fatal cerebral vasculitis after placoid pigment epitheliopathy. Histopathologic data revealed a focal granulomatous inflammation of medium-sized arteries in the leptomeninges. Multinucleated giant cells were a conspicuous part of the inflammatory reaction. The cause of both placoid pigment epitheliopathy and cerebral vasculitis remains obscure.
已有4例疑似脑动脉炎与急性后极部多灶性扁平状色素上皮病变相关的病例报道，但均未得到组织病理学证实。我们报告1例在扁平状色素上皮病变后发生致命性脑动脉炎的患者。组织病理学资料显示软脑膜中型动脉有局灶性肉芽肿性炎症。多核巨细胞是炎症反应的显著组成部分。扁平状色素上皮病变和脑动脉炎的病因仍不清楚。
