Climenhaga H, Macdonald J M, McCarey B E, Waring G O
Department of Ophthalmology, Emory University, School of Medicine, Atlanta, GA.
Arch Ophthalmol. 1988 Jun;106(6):818-24. doi: 10.1001/archopht.1988.01060130888047.
Impermeable, solid polysulfone intracorneal lenses (ICLs) can change corneal refractive power but will not allow diffusion of nutrients from the aqueous to the anterior stroma. Lenses of 4, 5, 6, and 7 mm in diameter were implanted in 50 cat eyes at depths ranging from 45% to 95% of corneal thickness to determine the effect of depth and diameter. Two types of stromal opacities occurred during follow-up: peripheral amorphous opacity (100%) and crystalline-granular lipid central opacity (79%). No eyes implanted with a 4-mm ICL ulcerated, but ulceration occurred in 28% of the eyes overall. Because opacification occurred with all lens diameters and implantation depths, metabolic demands of the cornea are not met. No safe limit exists at which these ICLs can be predictably used in cat eyes.
不可渗透的固体聚砜角膜内透镜（ICL）可改变角膜屈光力，但不允许营养物质从房水扩散至角膜前基质。将直径为4、5、6和7毫米的透镜植入50只猫眼中，植入深度为角膜厚度的45%至95%，以确定深度和直径的影响。随访期间出现了两种类型的基质混浊：周边无定形混浊（100%）和结晶颗粒状脂质中央混浊（79%）。植入4毫米ICL的眼睛均未发生溃疡，但总体上有28%的眼睛发生了溃疡。由于所有透镜直径和植入深度均出现混浊，角膜的代谢需求未得到满足。在猫眼中，不存在可预测地使用这些ICL的安全极限。
