Prakash R, Marwah S, Goel S C, Tuli S M
School of Biomedical Engineering, Institute of Technology, Banaras Hindu University, Varanasi, India.
Biomaterials. 1988 Mar;9(2):198-202. doi: 10.1016/0142-9612(88)90123-8.
An experimental study was undertaken to evaluate the suitability or otherwise of carbon fibre reinforced epoxy (CFRE) implants for bridging large osteoperiosteal gaps, devoid of periosteum. Using the basic principles of composite mechanics and simple design criteria, CFRE implants were designed and developed. These implants were put in simulated osteoperiosteal gaps in the ulna of healthy mature rabbits. Ten wk postoperative results clearly demonstrated that implants made of CFRE induced callus bone formation (in the form of woven bone) which totally encapsulated the implant thereby providing reunion of the two bone segments. Further follow-up showed formation of lamellar bones and formation in the pores of the implant. Radiological and scanning electron microscopical evidence is presented.
进行了一项实验研究，以评估碳纤维增强环氧树脂（CFRE）植入物用于桥接大的无骨膜骨膜间隙的适用性。利用复合材料力学的基本原理和简单的设计标准，设计并开发了CFRE植入物。将这些植入物置于健康成年兔尺骨的模拟骨膜间隙中。术后10周的结果清楚地表明，由CFRE制成的植入物诱导了骨痂骨形成（以编织骨的形式），该骨痂完全包裹了植入物，从而实现了两个骨段的愈合。进一步的随访显示有板层骨形成以及在植入物孔隙中的形成。给出了放射学和扫描电子显微镜证据。
