Peluso G, Ambrosio L, Cinquegrani M, Nicolais L, Saiello S, Tajana G
Institute of Protein Biochemistry and Enzimology - CNR, Naples, Italy.
Biomaterials. 1991 Mar;12(2):231-5. doi: 10.1016/0142-9612(91)90205-o.
The aim of this paper was to evaluate the histocompatibility of differently cured carbon fibre reinforced epoxy composites, studying their potential to induce an intolerance reaction in neighbouring tissues after peritoneal implantation in the rat. According to the microscopic and scanning electron microscope findings, the inductive capacity to generate connective tissue and cellular reaction was greatest in the partially cured material compared to the fully cured material. In addition, only the partially cured material implants appeared totally coated by macrophages at various stages of activation. The differences in the cellular reactions and scar tissue deposition in the interstices of these two composites are probably related to the chemical surface properties rather than to the structural characteristics of the materials.
本文旨在评估不同固化程度的碳纤维增强环氧树脂复合材料的组织相容性，研究其在大鼠腹膜植入后诱发邻近组织不耐受反应的可能性。根据显微镜和扫描电子显微镜的观察结果，与完全固化的材料相比，部分固化的材料生成结缔组织和细胞反应的诱导能力最强。此外，只有部分固化的材料植入物在不同激活阶段似乎完全被巨噬细胞覆盖。这两种复合材料间隙中的细胞反应和瘢痕组织沉积差异可能与材料的化学表面性质而非结构特征有关。
