Department of Plastic and Reconstructive Surgery, National Defense Medical College Hospital, Tokorozawa, Saitama, Japan, 359-8513, Japan.
Tissue Engineering and Wound Healing Laboratory, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School, MA 02115.
J Craniofac Surg. 2021;32(2):e189-e190. doi: 10.1097/SCS.0000000000007061.
This is the first report of multiple parosteal lipomas as a late complication of aesthetic procedures. A 70-year-old woman presented with multiple frontal nodules that had grown slowly over 5 years. She underwent forehead-lifting surgery 30 years ago and botulinum toxin injection 3 years ago. Computed tomography showed six low-density nodules measuring 10 to 20 mm just above the frontal bone. The tumors were resected via a parietal coronal incision. Histopathological findings revealed parosteal lipoma with foreign bodies. At 1 year postoperatively, there has been no recurrence or complications. The multiple lesions corresponded to the sites of the aesthetic procedures. The mesenchymal cells in the periosteum seemed to be stimulated by cytokines released from a postoperative hematoma or damaged periosteum, resulting in tumorigenesis. When performing aesthetic procedures in the face, care should be taken to avoid unnecessary injury to the periosteum, given the possibility of tumor development.Level of evidence: Level V, case report.
这是首例多发性骨旁脂肪瘤作为美容手术的晚期并发症的报告。一名 70 岁女性因额部缓慢生长的多个结节就诊，病史已有 5 年。她 30 年前曾行额部提升术，3 年前行肉毒毒素注射。计算机断层扫描显示额骨上方有 6 个直径 10 至 20 毫米的低密度结节。通过顶骨冠状切口切除肿瘤。组织病理学检查显示骨旁脂肪瘤伴异物。术后 1 年，无复发或并发症。多处病变与美容手术部位相对应。骨膜中的间充质细胞似乎受到术后血肿或受损骨膜释放的细胞因子的刺激，导致肿瘤发生。在面部进行美容手术时，鉴于肿瘤发生的可能性，应注意避免不必要的骨膜损伤。
病例报告，5 级。
