Department of Internal Medicine, Neurology Division, Universidade Federal do Ceará, Fortaleza, Brazil.
Department of Surgery, Neurology Division, Universidade Federal do Ceará, Fortaleza, Brazil.
J Spinal Cord Med. 2022 Nov;45(6):975-978. doi: 10.1080/10790268.2021.1878341. Epub 2021 Mar 11.
Spinal-generated movement disorders are a complex group of medical conditions, frequently misdiagnosed, originating in the spinal cord or from combined peripheral and central nervous system involvement. In this case report, we describe a novel form of position-dependent dyskinesia due to severe craniocervical malformation.
An 83-year-old woman with basilar invagination at the C2 vertebra above the line of Chamberlain, occipitocervical lordosis, platybasia with a short clivus, ankylosis of the C1-C2 complex and fusion of the C1 arch developed an unusual pattern of position-dependent left arm dyskinesia triggered by bending her neck forward with simultaneous contact of the flexed elbow with a flat surface. Symptoms did not improve with anticonvulsants and she progressed and died suddenly.
CONCLUSION/CLINICAL RELEVANCE: A newly described form of position-dependent arm dyskinesia can be associated with severe craniocervical malformation.
脊髓源性运动障碍是一组复杂的医学病症，常被误诊，其起源于脊髓或外周和中枢神经系统的联合受累。在本病例报告中，我们描述了一种因严重颅颈畸形引起的新型位置依赖运动障碍。
一位 83 岁女性，第 2 颈椎颅底凹陷，超过 Chamberlain 线，寰枢椎前凸，斜坡短小，C1-C2 复合体融合，C1 弓融合，出现了一种不寻常的位置依赖左手臂运动障碍模式，这种运动障碍是由颈部向前弯曲并同时使弯曲的肘部接触平面引起的。抗癫痫药物治疗没有改善症状，患者病情进展并突然死亡。
结论/临床相关性：一种新描述的位置依赖手臂运动障碍形式可能与严重的颅颈畸形有关。
