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在结核病诊所患者中筛查艾滋病毒 - 来自马拉维、赞比亚和津巴布韦基于人群的艾滋病毒影响评估调查的结果,2015-2016 年。

Screening for HIV Among Patients at Tuberculosis Clinics - Results from Population-Based HIV Impact Assessment Surveys, Malawi, Zambia, and Zimbabwe, 2015-2016.

出版信息

MMWR Morb Mortal Wkly Rep. 2021 Mar 12;70(10):342-345. doi: 10.15585/mmwr.mm7010a2.

Abstract

The World Health Organization and national guidelines recommend HIV testing and counseling at tuberculosis (TB) clinics for all patients, regardless of TB diagnosis (1). Population-based HIV Impact Assessment (PHIA) survey data for 2015-2016 in Malawi, Zambia, and Zimbabwe were analyzed to assess HIV screening at TB clinics among persons who had positive HIV test results in the survey. The analysis was stratified by history of TB diagnosis* (presumptive versus confirmed), awareness of HIV-positive status, antiretroviral therapy (ART) status, and viral load suppression among HIV-positive adults, by history of TB clinic visit. The percentage of adults who reported having ever visited a TB clinic ranged from 4.7% to 9.7%. Among all TB clinic attendees, the percentage who reported that they had received HIV testing during a TB clinic visit ranged from 48.0% to 62.1% across the three countries. Among adults who received a positive HIV test result during PHIA and who did not receive a test for HIV at a previous TB clinic visit, 29.4% (Malawi), 21.9% (Zambia), and 16.2% (Zimbabwe) reported that they did not know their HIV status at the time of the TB clinic visit. These findings represent missed opportunities for HIV screening and linkage to HIV care. In all three countries, viral load suppression rates were significantly higher among those who reported ever visiting a TB clinic than among those who had not (p<0.001). National programs could strengthen HIV screening at TB clinics and leverage them as entry points into the HIV diagnosis and treatment cascade (i.e., testing, initiation of treatment, and viral load suppression).

摘要

世界卫生组织和各国指南建议在结核病(TB)诊所对所有患者进行 HIV 检测和咨询,无论其 TB 诊断结果如何(1)。对马拉维、赞比亚和津巴布韦 2015-2016 年基于人群的 HIV 影响评估(PHIA)调查数据进行了分析,以评估在调查中 HIV 检测结果呈阳性的人群在 TB 诊所进行 HIV 筛查的情况。该分析按 TB 诊断史*(疑似与确诊)、HIV 阳性状态知晓情况、抗逆转录病毒治疗(ART)状况以及 HIV 阳性成人的病毒载量抑制情况进行分层,分层依据是 TB 诊所就诊史。报告曾去过 TB 诊所的成年人比例从 4.7%到 9.7%不等。在所有 TB 诊所就诊者中,报告在 TB 诊所就诊期间接受过 HIV 检测的比例在这三个国家分别为 48.0%至 62.1%。在 PHIA 中接受过阳性 HIV 检测结果且之前在 TB 诊所就诊时未接受 HIV 检测的成年人中,29.4%(马拉维)、21.9%(赞比亚)和 16.2%(津巴布韦)报告在 TB 诊所就诊时不知道自己的 HIV 状况。这些发现表明错过了 HIV 筛查和与 HIV 护理衔接的机会。在这三个国家中,报告曾去过 TB 诊所的成年人与未去过的成年人相比,病毒载量抑制率明显更高(p<0.001)。国家方案可以加强 TB 诊所的 HIV 筛查,并将其作为进入 HIV 诊断和治疗级联(即检测、治疗启动和病毒载量抑制)的切入点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0191/7951815/f8e23ba627ca/mm7010a2-F.jpg

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