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基于Agent 的疟疾控制模型:通过传统撒哈拉以南分组中蚊虫水生栖息地管理。

Agent-based modeling of malaria control through mosquito aquatic habitats management in a traditional sub-Sahara grouping.

机构信息

Department of Mathematics and Computer Science, Faculty of Science, University of Ngaoundere, Ngaoundere, Cameroon.

Departments of Mathematics and Computer Science, ENSAI, University of Ngaoundere, Ngaoundere, Cameroon.

出版信息

BMC Public Health. 2021 Mar 11;21(1):487. doi: 10.1186/s12889-020-10150-4.

Abstract

BACKGROUND

Africans pour dirty water around their houses which constitutes aquatic habitats (AH). These AH are sought by mosquitoes for larval development. Recent studies have shown the effectiveness of destroying AH around houses in reducing malaria incidence. An agent-based model is proposed for controlling malaria's incidence through population sensitizing campaigns on the harmful effects of AH around houses.

METHODS

The environment is constituted of houses, AH, mosquitoes, humans, and hospital. Malaria's spread dynamic is linked to the dynamics of humans and mosquitoes. The mosquito's dynamic is represented by egg-laying and seeking blood. The human's dynamic is animated by hitting mosquitoes. AH are destroyed each time by 10% of their starting number. The number of infected humans varied from 0-90 which led to a total of 1001 simulations.

RESULTS

When the number of houses and AH is equal, the results are approximate as the field data. At each reduction of AH, the incidence and prevalence tend more and more towards 0. When there is no AH and infected humans, the prevalence and incidence are at 0.

CONCLUSIONS

When there is no AH site, the disease disappears completely. Global destruction of AH in an environment and using many parameters in the same model are recommended.

摘要

背景

非洲人在他们的房屋周围倾倒污水,这些污水构成了水生栖息地(AH)。蚊子会在这些 AH 中寻找幼虫发育的场所。最近的研究表明,破坏房屋周围的 AH 可以有效降低疟疾的发病率。通过针对房屋周围 AH 的有害影响开展人群宣传活动,提出了一种基于代理的模型来控制疟疾的发病率。

方法

环境由房屋、AH、蚊子、人类和医院组成。疟疾的传播动态与人类和蚊子的动态相关联。蚊子的动态通过产卵和寻找血液来表示。人类的动态通过拍打蚊子来表现。每次会破坏 AH 的 10%,起始数量为 100。模拟总共有 1001 次,受感染的人类数量从 0 到 90 不等。

结果

当房屋和 AH 的数量相同时,结果与实地数据相近。每次减少 AH 的数量,发病率和患病率都越来越接近 0。当没有 AH 和受感染的人类时,发病率和患病率都为 0。

结论

当没有 AH 存在时,疾病就会完全消失。建议在同一模型中使用多种参数,对环境中的 AH 进行全球破坏。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae2c/7953772/1c575d9dd486/12889_2020_10150_Fig1_HTML.jpg

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