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青少年寻常痤疮酷似皮肤型红斑狼疮:1例罕见病例报告

Acne Vulgaris Mimicking Cutaneous Lupus Erythematosus in an Adolescent: Report of a Rare Case.

作者信息

Sitohang Irma Bernadette S, Rheza Agung Mohamad, Sirait Sondang P, Fitri Eyleny Meisyah, Suseno Lis Surachmiati

机构信息

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

出版信息

Case Rep Dermatol. 2021 Feb 1;13(1):69-74. doi: 10.1159/000511530. eCollection 2021 Jan-Apr.

DOI:10.1159/000511530
PMID:33708086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7923721/
Abstract

Acne vulgaris is a chronic and self-limiting disorder of the pilosebaceous unit which is primarily seen in adolescents. Acne vulgaris presents as polymorphic lesions, consisting of comedones, papules, pustules, cysts, nodules, scarring, and dyspigmentation. Acneiform presentation of cutaneous lupus erythematosus (CLE) is extremely rare. The presentation of CLE is notoriously diverse and often mimics a broad range of unrelated skin disorders. We present a case by referring to American College of Rheumatology (ACR) criteria for systemic lupus erythematosus (SLE); our patient's conditions did not meet any of the clinical criteria of the Systemic Lupus International Collaborating Clinics (SLICC) for SLE. Subsequent to thorough history-taking, physical examination, and laboratory evaluations, the diagnosis of acne vulgaris was established, and a diagnosis of CLE was excluded. As acneiform presentation of CLE is rare, we here present a case which resembled both acne vulgaris and CLE. We describe our experience in establishing the diagnosis of severe acne vulgaris accompanied by scars in a 12-year-old boy with a malar rash and scars on his frontal and malar area who had initially been misdiagnosed as having CLE. This unusual case highlights the broad spectrum of adolescent acne and the importance of clinical identification of the disease so that unnecessary workups might be avoided.

摘要

寻常痤疮是一种毛囊皮脂腺单位的慢性自限性疾病,主要见于青少年。寻常痤疮表现为多形性损害,包括粉刺、丘疹、脓疱、囊肿、结节、瘢痕和色素沉着。皮肤型红斑狼疮(CLE)的痤疮样表现极为罕见。CLE的表现极为多样,常常模仿一系列不相关的皮肤疾病。我们通过参考美国风湿病学会(ACR)系统性红斑狼疮(SLE)的标准来呈现一个病例;我们患者的病情不符合系统性红斑狼疮国际协作临床中心(SLICC)关于SLE的任何临床标准。在进行全面的病史采集、体格检查和实验室评估后,确诊为寻常痤疮,并排除了CLE的诊断。由于CLE的痤疮样表现罕见,我们在此呈现一个既类似寻常痤疮又类似CLE的病例。我们描述了在一名12岁男孩中诊断重度寻常痤疮伴瘢痕的经验,该男孩面颊部有皮疹,额部和面颊部有瘢痕,最初被误诊为CLE。这个不寻常的病例凸显了青少年痤疮的广泛谱系以及临床识别该疾病的重要性,以便避免不必要的检查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6b/7923721/5ce93cc7b80d/cde-0013-0069-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6b/7923721/666788369a60/cde-0013-0069-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6b/7923721/5ce93cc7b80d/cde-0013-0069-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6b/7923721/666788369a60/cde-0013-0069-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6b/7923721/5ce93cc7b80d/cde-0013-0069-g02.jpg

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Dermatol Pract Concept. 2023 Jan 1;13(1):e2023048. doi: 10.5826/dpc.1301a48.

本文引用的文献

1
Systemic lupus erythematosus camouflaging: As refractory acne in a young girl.系统性红斑狼疮伪装:表现为一名年轻女孩的难治性痤疮。
J Family Med Prim Care. 2019 Jan;8(1):276-279. doi: 10.4103/jfmpc.jfmpc_376_18.
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Acneiform eruptions.痤疮样疹。
Clin Dermatol. 2014 Jan-Feb;32(1):24-34. doi: 10.1016/j.clindermatol.2013.05.023.
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Managing adolescent acne: a guide for pediatricians.青少年痤疮的管理:儿科医生指南
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