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中国西部肺炎的临床特征及其与低钾血症的关系。

The clinical characteristics of pneumonia and its relationship between hypokalemia in west China.

作者信息

Han Zhoubo, Zhang Yong, Liao Shunli, Zhou Na

机构信息

Department of Pediatrics, The People's Hospital of Bishan District, Chongqing, China.

出版信息

Transl Pediatr. 2021 Feb;10(2):406-414. doi: 10.21037/tp-20-471.

Abstract

BACKGROUND

(MP) is one of the most common respiratory pathogens of community acquired pneumonia (CAP) in children. The purpose of this study was to identify epidemics of pneumonia (MPP) and to determine the relationship between hypokalemia and MPP.

METHODS

This study was retrospectively conducted from 1 August 2016 to 31 July 2018 at Bishan People's Hospital in Chongqing, China. We analyzed the demographic characteristics (age, gender), extra-pulmonary manifestations, fever duration, length of hospital stay, whole blood cell (WBC) count, C-reactive protein (CRP) levels, and lactate dehydrogenase (LDH) levels.

RESULTS

The total number of children with pneumonia was 3,385, including 570 (16.84%) patients in the MP infection group. The male-to-female ratio was 1.34:1. The peak time of MPP incidence was in autumn. The MP infection group had a significantly higher ratio of fever, higher body temperature, and longer fever duration. The number of MP-infected patients with hypokalemia was highest in spring. The length of hospital stay in the mild hypokalemia group was longer than in the normokalemia group. Furthermore, severe hypokalemia cases were all in the severe MP infection group, and the severity of MP infection and hypokalemia were positively correlated.

CONCLUSIONS

In this study, we concluded that children infected with MP were more susceptible to fever, and had a longer duration of fever. The number of MP-infected patients with mild hypokalemia peaked in spring, and affected more boys than girls. Furthermore, patients with severe hypokalemia had longer fever duration, and a correlation was found between the severity of MP infection and hypokalemia.

摘要

背景

支原体肺炎(MP)是儿童社区获得性肺炎(CAP)最常见的呼吸道病原体之一。本研究旨在识别支原体肺炎(MPP)的流行情况,并确定低钾血症与MPP之间的关系。

方法

本研究于2016年8月1日至2018年7月31日在中国重庆璧山人民医院进行回顾性研究。我们分析了人口统计学特征(年龄、性别)、肺外表现、发热持续时间、住院时间、全血细胞(WBC)计数、C反应蛋白(CRP)水平和乳酸脱氢酶(LDH)水平。

结果

肺炎患儿总数为3385例,其中MP感染组570例(16.84%)。男女比例为1.34:1。MPP发病高峰时间为秋季。MP感染组发热比例、体温更高、发热持续时间更长。MP感染合并低钾血症的患者数量在春季最高。轻度低钾血症组的住院时间比正常血钾组更长。此外,重度低钾血症病例均在重度MP感染组,MP感染的严重程度与低钾血症呈正相关。

结论

在本研究中,我们得出结论,感染MP的儿童更容易发热,且发热持续时间更长。MP感染合并轻度低钾血症的患者数量在春季达到峰值,且男孩受影响多于女孩。此外,重度低钾血症患者发热持续时间更长,且发现MP感染的严重程度与低钾血症之间存在相关性。

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