School of Chemistry and Physics, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4000, South Africa.
Int J Dermatol. 2021 Sep;60(9):1082-1091. doi: 10.1111/ijd.15502. Epub 2021 Mar 12.
This review article seeks to provide an overview of allergic contact dermatitis (ACD) as a significant environmental and occupational skin disease, the phases of ACD, its causes from the occupational and environmental perspectives, its detection, the effects of ACD with respect to the social, psychological, occupational, and financial perspectives, and its cure and/or prevention. Human skin is very sensitive and as the largest organ in the body, it is highly prone to direct and indirect contact with the substances from its environment. The skin reacts to these substances (xenobiotics) differently depending on the individual's tolerance level or threshold. Allergic contact dermatitis is a significant environmental and occupational skin disease that should not be ignored in our society because it can affect the quality of life of an affected individual. There are multiple causes of ACD, and these causes of ACD have been discussed from two perspectives: environmental and occupational. The effects of ACD can be psychological, social, financial, and occupational. There is need for more public enlightenment on the effects of ACD as well as a precise understanding that it is not a contagious disease so as to significantly reduce the psychological and social effects of ACD on these patients.
这篇综述文章旨在概述变应性接触性皮炎（ACD）作为一种重要的环境和职业性皮肤病，ACD 的各个阶段，从职业和环境角度来看其病因，检测方法，从社会、心理、职业和经济角度来看 ACD 的影响，以及其治疗和/或预防方法。人类皮肤非常敏感，作为身体最大的器官，它很容易与来自环境的物质直接或间接接触。皮肤对这些物质（外源性物质）的反应因人而异，取决于个体的耐受水平或阈值。变应性接触性皮炎是一种重要的环境和职业性皮肤病，在我们的社会中不容忽视，因为它会影响到受影响个体的生活质量。ACD 有多种病因，这些病因已从环境和职业两个角度进行了讨论。ACD 的影响可能是心理上、社会上、经济上和职业上的。需要加强对 ACD 影响的公众教育，并明确认识到它不是一种传染病，以显著减轻 ACD 对这些患者的心理和社会影响。
