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在非允许温度下,T4噬菌体感染大肠杆菌dnaEts诱导细胞分裂。

Stimulation of cell division by T4 infection in Escherichia coli dnaEts at nonpermissive temperature.

作者信息

Sato K, Sekiguchi M

出版信息

Mol Gen Genet. 1977 Sep 21;155(1):1-5. doi: 10.1007/BF00268554.

Abstract

Filamentous cells resulting from growth of a dnaEts mutant of Escherichia coli at high temperature were stimulated to divide by infection with bacteriophage T4. The effect appears to be related to T4 DNA synthesis; no increase in cell number took place in chloramphenicol-treated. T4-infected cells nor in cells infected with DNA synthesis-less mutants of T4. The ability of cells to divide after T4 infection was dependent on the length of time that the cells had been grown at 42 degrees C, indicating that a potential for cell division accumulates during preincubation.

摘要

大肠杆菌dnaEts突变体在高温下生长产生的丝状细胞通过噬菌体T4感染被刺激分裂。这种效应似乎与T4 DNA合成有关;用氯霉素处理的T4感染细胞或感染T4 DNA合成缺陷突变体的细胞中细胞数量没有增加。T4感染后细胞的分裂能力取决于细胞在42℃下生长的时间长度,这表明在预培养期间细胞分裂的潜能会积累。

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