Buckley P J, Kosturko L D, Kozinski A W
Proc Natl Acad Sci U S A. 1972 Nov;69(11):3165-9. doi: 10.1073/pnas.69.11.3165.
An RNA-DNA copolymer was isolated from Escherichia coli infected with bacteriophage T4. The RNA and DNA are covalently linked, and in the same polynucleotide strand. The DNA of the copolymer hybridizes specifically to the left strand of phage T4 DNA. The copolymer is produced in cells infected with amber mutants of phage T4 deficient in DNA replication and is not inhibited by the addition of chloramphenicol.
从感染了噬菌体T4的大肠杆菌中分离出一种RNA-DNA共聚物。RNA和DNA共价连接，且位于同一条多核苷酸链中。该共聚物的DNA与噬菌体T4 DNA的左链特异性杂交。这种共聚物在感染了DNA复制缺陷的噬菌体T4琥珀突变体的细胞中产生，并且不受氯霉素添加的抑制。
