Wang Yuqiu, Guo Maoze, He Bingfang, Gao Bingbing
College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China.
School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211816, China.
Anal Chem. 2021 Mar 23;93(11):4687-4696. doi: 10.1021/acs.analchem.0c04956. Epub 2021 Mar 14.
Intelligent wound patches have the potential properties of ultra-adhesion, self-healing ability, biosensing, antibacterial, anti-inflammatory, etc. In situ sensing (biosensing and monitoring) and intelligent drug delivery deserve more exploration, and new strategies of these two factors are of great importance. In this Feature, a comprehensive set of the progress in the area of intelligent wound patches, especially those based on multiple biosensing and electronics, and their potentials in drug release is deliberated. In addition, the major challenges in this field and opinions on its future developments are portrayed.
智能伤口贴片具有超粘附、自愈能力、生物传感、抗菌、抗炎等潜在特性。原位传感(生物传感和监测)和智能药物递送值得更多探索,这两个因素的新策略至关重要。在本专题中,我们深入探讨了智能伤口贴片领域的全面进展,特别是基于多重生物传感和电子技术的贴片及其在药物释放方面的潜力。此外,还描述了该领域的主要挑战及其未来发展的观点。