Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
King's Centre for Global Health & Health Partnerships, School of Population Health & Environmental Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Eur J Contracept Reprod Health Care. 2021 Jun;26(3):175-183. doi: 10.1080/13625187.2021.1879783. Epub 2021 Mar 10.
To conduct a secondary analysis of continuation, unwanted effects and cost consequences at 1 year in copper intrauterine device (IUD) users aged under 30 in the European Active Surveillance Study for Intrauterine Devices (EURAS-IUD study) based on IUD type.
Descriptive and comparative analyses of copper IUD continuation, unwanted effects and estimated cost consequences at 1 year were performed in users aged under 30 based on IUD copper surface area, shape or design, width and arms' flexibility.
5796 copper IUD users were identified to have been aged under 30 at EURAS-IUD study recruitment and data for 5762 users (99.4%) was analysed. Higher IUD continuation, fewer unwanted effects and lower costs were observed with IUDs of the lowest copper content (<300mm), horse-shoe frame design, widths 18 mm to <30mm and flexible IUD arms. Discontinuation, unwanted effects and costs were greater with frameless IUDs and framed, ≥30mm width IUDs with 380mm of copper and copper bands on their rigid transverse IUD arms.
Significant differences in continuation, reported unwanted effects and estimated costs at 1 year between IUD types were observed in users aged under 30. Although further research is needed, clinicians should consider these findings when counselling and choosing IUD types for younger women.
基于宫内节育器（IUD）类型，对欧洲主动监测宫内节育器研究（EURAS-IUD 研究）中年龄在 30 岁以下的铜 IUD 用户的 1 年续用率、不良事件和成本后果进行二次分析。
根据铜表面积、形状或设计、宽度和臂的柔韧性，对年龄在 30 岁以下的铜 IUD 用户的 1 年续用率、不良事件和估计成本后果进行描述性和对比分析。
EURAS-IUD 研究招募时确定了 5796 名年龄在 30 岁以下的铜 IUD 用户，其中 5762 名（99.4%）用户的数据进行了分析。铜含量最低（<300mm）、马蹄形框架设计、18mm 至<30mm 宽度和柔韧性臂的 IUD 具有更高的续用率、更少的不良事件和更低的成本。无框架 IUD、框架、宽度≥30mm 且具有 380mm 铜和刚性横向 IUD 臂上的铜带的 IUD 具有更高的停用率、不良事件和成本。
在年龄在 30 岁以下的用户中，观察到不同类型 IUD 在 1 年时的续用率、报告的不良事件和估计的成本存在显著差异。尽管还需要进一步研究，但临床医生在为年轻女性咨询和选择 IUD 类型时应考虑这些发现。
