健康与疾病中的肠道真菌群：从失衡到临床机遇
Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities.
作者信息
Wu Xiaoyan, Xia Yaoyao, He Fang, Zhu Congrui, Ren Wenkai
机构信息
State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Laboratory of Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou, 510642, China.
College of Animal Science and Technology, Southwest University, Chongqing, 400716, China.
出版信息
Microbiome. 2021 Mar 14;9(1):60. doi: 10.1186/s40168-021-01024-x.
Bacteria, viruses, protozoa, and fungi establish a complex ecosystem in the gut. Like other microbiota, gut mycobiota plays an indispensable role in modulating intestinal physiology. Notably, the most striking characteristics of intestinal fungi are their extraintestinal functions. Here, we provide a comprehensive review of the importance of gut fungi in the regulation of intestinal, pulmonary, hepatic, renal, pancreatic, and brain functions, and we present possible opportunities for the application of gut mycobiota to alleviate/treat human diseases. Video Abstract.
细菌、病毒、原生动物和真菌在肠道中建立了一个复杂的生态系统。与其他微生物群一样，肠道真菌群在调节肠道生理方面发挥着不可或缺的作用。值得注意的是，肠道真菌最显著的特征是它们的肠外功能。在此，我们全面综述了肠道真菌在调节肠道、肺、肝、肾、胰腺和脑功能中的重要性，并提出了应用肠道真菌群来缓解/治疗人类疾病的可能机会。视频摘要。
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