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前列腺腺癌组织病理学类型与肿瘤分级的关系分析

Analysis of Prostate Adenocarcinoma Histopathological Types in Relation to Tumor Grade.

作者信息

PĂnuŞ Andrei, Simionescu Cristiana Eugenia, DrĂgoescu Petru Octavian, Tomescu Paul, Stepan Alex Emilian

机构信息

PhD Student, Department of Pathology, University of Medicine and Pharmacy of Craiova, Romania.

Department of Pathology, University of Medicine and Pharmacy of Craiova, Romania.

出版信息

Curr Health Sci J. 2020 Oct-Dec;46(4):405-411. doi: 10.12865/CHSJ.46.04.12. Epub 2020 Dec 31.

Abstract

Prostate adenocarcinomas are some of the most common malignancies diagnosed in men, and the evaluation of tumor growth patterns is the basis for establishing the aggressiveness of the lesions. The study included 283 cases of prostate adenocarcinomas for which histopathological type and tumor grade were analyzed. The results indicated the association of ductal, sarcomatoid and signet ring-like cell types with aggressive growth patterns and high scores, atrophic and pseudohyperplastic types with mild growth patterns and low scores, foamy gland type presented intermediate growth patterns/scores, while conventional and colloid types had variable aspects. The grading systems used may be considered consistent with the histological types of prostate adenocarcinomas.

摘要

前列腺腺癌是男性中诊断出的最常见恶性肿瘤之一,评估肿瘤生长模式是确定病变侵袭性的基础。该研究纳入了283例前列腺腺癌病例,对其组织病理学类型和肿瘤分级进行了分析。结果表明,导管型、肉瘤样型和印戒样细胞型与侵袭性生长模式及高分相关,萎缩型和假增生型与轻度生长模式及低分相关,泡沫腺型呈现中等生长模式/分数,而传统型和胶样型则具有不同表现。所使用的分级系统可被认为与前列腺腺癌的组织学类型一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b2d/7948024/39c99b677d8c/CHSJ-46-04-405-fig1.jpg

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