• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

前列腺腺癌组织病理学类型与肿瘤分级的关系分析

Analysis of Prostate Adenocarcinoma Histopathological Types in Relation to Tumor Grade.

作者信息

PĂnuŞ Andrei, Simionescu Cristiana Eugenia, DrĂgoescu Petru Octavian, Tomescu Paul, Stepan Alex Emilian

机构信息

PhD Student, Department of Pathology, University of Medicine and Pharmacy of Craiova, Romania.

Department of Pathology, University of Medicine and Pharmacy of Craiova, Romania.

出版信息

Curr Health Sci J. 2020 Oct-Dec;46(4):405-411. doi: 10.12865/CHSJ.46.04.12. Epub 2020 Dec 31.

DOI:10.12865/CHSJ.46.04.12
PMID:33717516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7948024/
Abstract

Prostate adenocarcinomas are some of the most common malignancies diagnosed in men, and the evaluation of tumor growth patterns is the basis for establishing the aggressiveness of the lesions. The study included 283 cases of prostate adenocarcinomas for which histopathological type and tumor grade were analyzed. The results indicated the association of ductal, sarcomatoid and signet ring-like cell types with aggressive growth patterns and high scores, atrophic and pseudohyperplastic types with mild growth patterns and low scores, foamy gland type presented intermediate growth patterns/scores, while conventional and colloid types had variable aspects. The grading systems used may be considered consistent with the histological types of prostate adenocarcinomas.

摘要

前列腺腺癌是男性中诊断出的最常见恶性肿瘤之一,评估肿瘤生长模式是确定病变侵袭性的基础。该研究纳入了283例前列腺腺癌病例,对其组织病理学类型和肿瘤分级进行了分析。结果表明,导管型、肉瘤样型和印戒样细胞型与侵袭性生长模式及高分相关,萎缩型和假增生型与轻度生长模式及低分相关,泡沫腺型呈现中等生长模式/分数,而传统型和胶样型则具有不同表现。所使用的分级系统可被认为与前列腺腺癌的组织学类型一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b2d/7948024/8829c25ed682/CHSJ-46-04-405-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b2d/7948024/39c99b677d8c/CHSJ-46-04-405-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b2d/7948024/8829c25ed682/CHSJ-46-04-405-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b2d/7948024/39c99b677d8c/CHSJ-46-04-405-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b2d/7948024/8829c25ed682/CHSJ-46-04-405-fig2.jpg

相似文献

1
Analysis of Prostate Adenocarcinoma Histopathological Types in Relation to Tumor Grade.前列腺腺癌组织病理学类型与肿瘤分级的关系分析
Curr Health Sci J. 2020 Oct-Dec;46(4):405-411. doi: 10.12865/CHSJ.46.04.12. Epub 2020 Dec 31.
2
Histopathological Study of the Prostate Cancer Growth Patterns in Relation with the Grading Systems.前列腺癌生长模式与分级系统关系的组织病理学研究
Curr Health Sci J. 2022 Jan-Mar;48(1):95-101. doi: 10.12865/CHSJ.48.01.14. Epub 2022 Mar 31.
3
Histologic classification of prostate cancer.前列腺癌的组织学分类。
Anal Quant Cytopathol Histpathol. 2015 Feb;37(1):39-47.
4
Usual and unusual histologic patterns of high Gleason score 8 to 10 adenocarcinoma of the prostate in needle biopsy tissue.前列腺针芯活检组织中高 Gleason 评分 8 至 10 分腺癌的常见和不常见组织学形态。
Am J Surg Pathol. 2012 Jun;36(6):900-7. doi: 10.1097/PAS.0b013e3182495dee.
5
Pseudohyperplastic Adenocarcinoma With Foamy Changes in Needle Prostate Biopsy and Prostatectomy.针吸前列腺活检及前列腺切除标本中出现泡沫样改变的假增生性腺癌
Int J Surg Pathol. 2016 Sep;24(6):477-82. doi: 10.1177/1066896916640360. Epub 2016 Mar 28.
6
Pseudohyperplastic prostate adenocarcinoma with signet ring cells mimicking hyperplastic colonic polyp and associated high grade foamy gland carcinoma. A case report.伴有印戒细胞的假增生性前列腺腺癌,酷似增生性结肠息肉,并伴有高级别泡沫状腺癌。病例报告。
Pathol Res Pract. 2014 May;210(5):325-7. doi: 10.1016/j.prp.2014.01.012. Epub 2014 Feb 12.
7
Histological variants of prostatic carcinoma and their significance.前列腺癌的组织学变异及其意义。
Histopathology. 2012 Jan;60(1):59-74. doi: 10.1111/j.1365-2559.2011.04039.x.
8
High-grade foamy gland prostatic adenocarcinoma on biopsy or transurethral resection: a morphologic study of 55 cases.活检或经尿道切除标本中的高级别泡沫状腺前列腺腺癌:55例形态学研究
Am J Surg Pathol. 2009 Apr;33(4):583-90. doi: 10.1097/PAS.0b013e31818a5c6c.
9
Foamy gland adenocarcinoma of the prostate: incidence, Gleason grade, and early clinical outcome.前列腺泡沫状腺腺癌:发病率、格里森分级和早期临床结局。
Hum Pathol. 2012 Jul;43(7):974-9. doi: 10.1016/j.humpath.2011.09.009. Epub 2012 Jan 4.
10
Histologic features of pseudohyperplastic perineural invasion in prostatic adenocarcinoma: a mimicker of benign hyperplastic glands and high-grade prostatic intraepithelial neoplasia.前列腺腺癌中假假性神经周围侵犯的组织学特征:良性增生腺体和高级别前列腺上皮内瘤的类似物。
Am J Surg Pathol. 2014 Jun;38(6):852-7. doi: 10.1097/PAS.0000000000000193.

本文引用的文献

1
Prostate cancer mortality projections reach a new high: With prostate cancer deaths projected to rise to their highest level in 20 years, some experts worry that changes to screening guidelines made in 2012 could be a factor.前列腺癌死亡率预测达到新高:预计前列腺癌死亡人数将升至20年来的最高水平,一些专家担心2012年筛查指南的改变可能是一个因素。
Cancer. 2020 Sep 1;126(17):3893-3894. doi: 10.1002/cncr.33127.
2
Prostate cancer growth patterns beyond the Gleason score: entering a new era of comprehensive tumour grading.前列腺癌的 Gleason 评分之外的生长模式:进入全面肿瘤分级的新时代。
Histopathology. 2020 Dec;77(6):850-861. doi: 10.1111/his.14214. Epub 2020 Sep 13.
3
European cancer mortality predictions for the year 2020 with a focus on prostate cancer.
欧洲 2020 年癌症死亡率预测,重点关注前列腺癌。
Ann Oncol. 2020 May;31(5):650-658. doi: 10.1016/j.annonc.2020.02.009. Epub 2020 Apr 19.
4
Cancer statistics, 2020.癌症统计数据,2020 年。
CA Cancer J Clin. 2020 Jan;70(1):7-30. doi: 10.3322/caac.21590. Epub 2020 Jan 8.
5
Prostatic Adenocarcinoma: A Grading from Gleason to the New Grade-Group System: A Historical and Critical Review.前列腺腺癌:从 Gleason 分级到新的分级组系统的分级:历史与批判性综述
Asian Pac J Cancer Prev. 2019 Mar 26;20(3):661-666. doi: 10.31557/APJCP.2019.20.3.661.
6
Grading of prostate cancer: a work in progress.前列腺癌分级:一项正在进行中的工作。
Histopathology. 2019 Jan;74(1):146-160. doi: 10.1111/his.13767.
7
Prostate Cancer Pathology: Recent Updates and Controversies.前列腺癌病理学:近期进展与争议
Mo Med. 2018 Mar-Apr;115(2):151-155.
8
Prostate cancer grading: a decade after the 2005 modified system.前列腺癌分级:2005 年修订系统十年后。
Mod Pathol. 2018 Jan;31(S1):S47-63. doi: 10.1038/modpathol.2017.133.
9
Histopathology of Prostate Cancer.前列腺癌的组织病理学。
Cold Spring Harb Perspect Med. 2017 Oct 3;7(10):a030411. doi: 10.1101/cshperspect.a030411.
10
From Gleason to International Society of Urological Pathology (ISUP) grading of prostate cancer.从前列腺癌的格里森分级到国际泌尿病理学会(ISUP)分级
Scand J Urol. 2016 Oct;50(5):325-9. doi: 10.1080/21681805.2016.1201858. Epub 2016 Jul 14.