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经乙状窦后入路切除巨大脑桥外侧室管膜瘤:二维手术视频

Retrosigmoid Approach for Resecting a Giant Lateral Pontine Ependymoma: Two-Dimensional Operative Video.

作者信息

Wang Hongxiang, Yan Yong, Xu Tao, Chen Juxiang

机构信息

Department of Neurosurgery, Changzheng Hospital, Naval Medical University, Neurosurgical Institute of Shanghai, Neurosurgical Institute of People's Liberation Army, Shanghai, China.

出版信息

J Neurol Surg B Skull Base. 2021 Feb;82(Suppl 1):S53-S54. doi: 10.1055/s-0040-1705158. Epub 2020 Sep 17.

Abstract

Ependymoma is one of the most common pediatric tumors in central nervous system, for which gross total resection has been the most favorable prognostic factor. 1 2 However, surgery of ependymomas located in brain stem is significantly challenging. This video demonstrates the microsurgical removal of an ependymoma originating from ependymal cells of the lateral recess of fourth ventricle via retrosigmoid approach in an 11-year-old female. The patient presented with a 6-month history of continues headache and vomiting. On examination, she had a walking instability and an emaciated body. Neuroimaging revealed a right lateral pontine lesion extending to the cerebellopontine angle region. The patient underwent a suboccipital craniotomy, followed by excellent exposure for the tumor. Petrosal vein encased by the tumor mass and close adhesion of the tumor and the initial segments of facial and acoustic nerves adjoined brain stem could be seen operatively. While preserving trigeminal nerve, facial and acoustic nerves, posterior cranial nerves, anterior inferior cerebellar artery, labyrinth artery, posterior inferior cerebellar artery, and petrosal vein, gross total resection was achieved under the careful operation along arachnoid spaces together with intratumoral decompression. The patient tolerated the procedure well without any neurological deficits. Histological examination confirmed the tumor as an ependymoma (WHO II). The cytology measurement of the cerebrospinal fluid did not find any tumor cells. Postoperative computed tomography and magnetic resonance imaging scan depicted complete resection of the tumor, and adjuvant radiotherapy was recommended. She remained symptom-free without any evidence of recurrence during the follow-up period of 1 year. Informed consent was obtained from the patient. The link to the video can be found at: https://youtu.be/sZ9GhUeltwc .

摘要

室管膜瘤是中枢神经系统最常见的儿童肿瘤之一,对于该肿瘤,肉眼全切除一直是最有利的预后因素。然而,位于脑干的室管膜瘤手术极具挑战性。本视频展示了一名11岁女性患者通过乙状窦后入路显微手术切除起源于第四脑室侧隐窝室管膜细胞的室管膜瘤。患者有持续6个月的头痛和呕吐病史。检查发现她行走不稳且身体消瘦。神经影像学检查显示右侧脑桥外侧病变延伸至桥小脑角区。患者接受了枕下开颅手术,随后对肿瘤进行了良好暴露。术中可见肿瘤包裹岩静脉,肿瘤与面神经和听神经起始段紧密粘连并毗邻脑干。在保留三叉神经、面神经、听神经、后组颅神经、小脑前下动脉、迷路动脉、小脑后下动脉和岩静脉的同时,沿着蛛网膜间隙小心操作并进行瘤内减压,实现了肉眼全切除。患者对手术耐受良好,无任何神经功能缺损。组织学检查证实肿瘤为室管膜瘤(世界卫生组织II级)。脑脊液细胞学检查未发现任何肿瘤细胞。术后计算机断层扫描和磁共振成像扫描显示肿瘤完全切除,建议进行辅助放疗。在1年的随访期内,她无症状,无任何复发迹象。已获得患者的知情同意。视频链接可在:https://youtu.be/sZ9GhUeltwc 找到。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fc0/7936043/a86feb11dc35/10-1055-s-0040-1705158-i190227ov-1.jpg

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