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炎症性肠病患者的童年创伤、抑郁、韧性和自杀风险。

Childhood trauma, depression, resilience and suicide risk in individuals with inflammatory bowel disease.

机构信息

Queen's University, Canada.

McMaster University, Canada.

出版信息

J Health Psychol. 2022 Jun;27(7):1626-1634. doi: 10.1177/1359105321999085. Epub 2021 Mar 15.

Abstract

Despite the prevalence of suicide risk in inflammatory bowel disease populations, research has yet to examine associations between childhood trauma, resilience, depression and suicide risk. In the present online study, 172 participants responded to measures of childhood trauma, resilience, depression and suicide risk. A moderated mediation revealed that resilience does not moderate the associations between childhood trauma, depressive symptoms and suicide risk. However, a serial mediation revealed that childhood trauma is associated with decreased resilience, which is related to higher depressive symptoms, and ultimately higher suicide risk, thus suggesting resilience and depression as significant intervention targets.

摘要

尽管炎症性肠病患者的自杀风险普遍存在,但研究尚未探讨儿童期创伤、韧性、抑郁和自杀风险之间的关联。在本项在线研究中,172 名参与者对儿童期创伤、韧性、抑郁和自杀风险进行了评估。调节中介分析显示,韧性不能调节儿童期创伤、抑郁症状和自杀风险之间的关系。然而,序列中介分析显示,儿童期创伤与韧性降低有关,而韧性降低与更高的抑郁症状有关,最终与更高的自杀风险有关,这表明韧性和抑郁是重要的干预靶点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed70/9092906/78caf8324efb/10.1177_1359105321999085-fig1.jpg

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