Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02215. Email:
Am J Manag Care. 2021 Mar 1;27(3):e80-e88. doi: 10.37765/ajmc.2021.88602.
To compare use of diabetes medications between beneficiaries enrolled in Medicare Advantage (MA) and traditional Medicare (TM).
Retrospective cohort analysis of Medicare enrollment and Part D event claims during 2015-2016.
Data came from 1,027,884 TM and 838,420 MA beneficiaries who received at least 1 prescription for an oral or injectable diabetes medication. After matching MA and TM enrollees by demographic characteristics and geography, we analyzed use of medication overall, choices of first diabetes medication for those new to medication, and patterns of adding medications.
Overall and for patients on 1, 2, or 3 diabetes medications, use of metformin was higher in MA by about 3 percentage points, but use of newer medication classes was 5.1 percentage points higher in TM overall (21.3% vs 16.2%). Use of guideline-recommended first-line agents was higher in MA. For those who started metformin first, use of a sulfonylurea as a second medication was 7.8 percentage points higher in MA than TM (61.5% vs 53.7%), whereas use of medications from newer classes was 7.7 percentage points lower (22.0% vs 29.7%). Mean total spending was $149 higher in TM for those taking 1 medication and $298 higher for those taking 2 medications. Differences in spending among MA plans were of similar magnitude to the MA-TM differences.
MA enrollees are more likely to be treated with metformin and sulfonylureas and less likely to receive costly newer medications than those in TM, but there also is substantial variation within MA. A limitation of the study is that we could not assess glucose control using glycated hemoglobin levels.
比较参加联邦医疗保险优势计划(MA)和传统联邦医疗保险(TM)的受益人的糖尿病药物使用情况。
对 2015-2016 年联邦医疗保险参保和部分 D 事件索赔进行回顾性队列分析。
数据来自 1027884 名 TM 和 838420 名 MA 受益人,他们至少开了 1 种口服或注射糖尿病药物处方。在通过人口统计学特征和地理位置匹配 MA 和 TM 参保人后,我们分析了总体药物使用情况、首次使用药物的新患者选择以及添加药物的模式。
总体而言,对于服用 1、2 或 3 种糖尿病药物的患者,MA 中使用二甲双胍的比例高出约 3 个百分点,但 TM 总体上使用更新的药物类别高出 5.1 个百分点(21.3%对 16.2%)。MA 中更常使用指南推荐的一线药物。对于首先开始使用二甲双胍的患者,MA 中使用磺酰脲类药物作为第二种药物的比例比 TM 高 7.8 个百分点(61.5%对 53.7%),而使用更新药物类别的比例低 7.7 个百分点(22.0%对 29.7%)。服用 1 种药物的 TM 患者的总花费比 MA 高 149 美元,服用 2 种药物的 TM 患者的总花费比 MA 高 298 美元。MA 计划之间的支出差异与 MA-TM 差异相似。
与 TM 相比,MA 参保人更有可能接受二甲双胍和磺酰脲类药物治疗,而不太可能接受昂贵的新药,但 MA 内也存在大量差异。该研究的一个局限性是我们无法使用糖化血红蛋白水平评估血糖控制情况。