Sostman D, Rockwell S, Smith G J, Gore J C, Kennedy K A, Habib A, Fischer J J, Armitage I M, Holcomb W
Department of Diagnostic Radiology, Yale University School of Medicine.
Invest Radiol. 1988 Apr;23(4):277-88. doi: 10.1097/00004424-198804000-00007.
We studied histology, findings on H-1 magnetic resonance (MR) imaging, and correlations of P-31 MR spectroscopy with microelectrode pH and pO2 measurements in the BA1112 rhabdomyosarcoma in WAG/Rij/Y rats. Intratumoral hemorrhage was a prominent feature on MR images and pathologic specimens. Eosinophilic necrosis could be seen microscopically but was not discernible on images. The peaks seen on P-31 MR spectra were similar to those reported in other tumors. The intratumoral pH was neutral despite low pO2 values and P-31 MR evidence for impaired metabolic status.
我们研究了WAG/Rij/Y大鼠BA1112横纹肌肉瘤的组织学、H-1磁共振（MR）成像结果，以及P-31 MR波谱与微电极pH和pO2测量值之间的相关性。瘤内出血是MR图像和病理标本上的一个突出特征。嗜酸性坏死在显微镜下可见，但在图像上无法辨别。P-31 MR波谱上看到的峰与其他肿瘤中报道的相似。尽管pO2值较低且P-31 MR有代谢状态受损的证据，但瘤内pH呈中性。
