Department of Medicine, King Abdulaziz University; Inflammatory Bowel Disease Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.
Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Saudi J Gastroenterol. 2021 Mar-Apr;27(2):91-96. doi: 10.4103/sjg.SJG_371_20.
Crohn's disease (CD) is a progressive illness associated with high morbidity owing to the complications associated with the condition. Patients' awareness and cognition of such complications may carry significant psychological impact. The aim of this study is to assess the illness cognition of Saudi patients diagnosed with CD and to identify clinical associations.
Adult patients with CD were asked to complete an illness cognition questionnaire (ICQ) between January and December of 2019. Additional data was extracted from the medical records. The ICQ composed of three domains: Helplessness (6 items), acceptance (6 items), and perceived benefits (6 items). Descriptive statistics were used to summarize patient characteristics and a linear regression analysis was used to identify associations with the ICQ score.
A total of 88 patients were included, of which 55.8% were females, 18% were smokers, and 11.5% had undergone CD-related surgery. The mean age was 26.9 ± 7.7 years and the mean duration of disease was 54.7 ± 60.5 months. The mean score was 17.4 ± 3.6 for the helplessness domain, 13.4 ± 3.6 for the acceptance domain, and 13.5 ± 3.5 for the perceived benefits domain. We found associations between abdominal pain and acceptance (P = 0.048), extra intestinal manifestations and perceived benefit (P = 0.001), and treatment with mesalamine and helplessness (P = 0.03). In a linear regression analysis, albumin level was the only factor associated with helplessness (coef = 0.18, P = 0.048).
A considerable proportion of Saudi patients diagnosed with CD generally reported a negative perception of their disease. Albumin level was associated with helplessness.
克罗恩病（CD）是一种进行性疾病，由于与该病相关的并发症，其发病率很高。患者对这些并发症的认识和认知可能会产生重大的心理影响。本研究旨在评估沙特 CD 患者的疾病认知，并确定其临床相关性。
2019 年 1 月至 12 月期间，我们邀请成年 CD 患者完成疾病认知问卷（ICQ）。还从病历中提取了其他数据。ICQ 由三个部分组成：无助感（6 项）、接受度（6 项）和感知益处（6 项）。使用描述性统计数据来总结患者特征，并使用线性回归分析来识别与 ICQ 评分相关的因素。
共纳入 88 例患者，其中 55.8%为女性，18%为吸烟者，11.5%接受过 CD 相关手术。患者的平均年龄为 26.9 ± 7.7 岁，疾病平均病程为 54.7 ± 60.5 个月。无助感域、接受域和感知获益域的平均得分为 17.4 ± 3.6、13.4 ± 3.6 和 13.5 ± 3.5。我们发现腹痛与接受度之间存在关联（P = 0.048），肠外表现与感知益处之间存在关联（P = 0.001），美沙拉嗪治疗与无助感之间存在关联（P = 0.03）。在线性回归分析中，白蛋白水平是与无助感唯一相关的因素（系数=0.18，P = 0.048）。
相当一部分沙特 CD 患者对疾病的认知普遍较为消极。白蛋白水平与无助感相关。
