Neihumicin, a new cytotoxic antibiotic from Micromonospora neihuensis. I. The producing organism, fermentation, isolation and biological properties.
作者信息
Wu R Y, Yang L M, Yokoi T, Lee K H
机构信息
Institute of Botany, Academia Sinica, Taipei, Taiwan, Republic of China.
出版信息
J Antibiot (Tokyo). 1988 Apr;41(4):481-7. doi: 10.7164/antibiotics.41.481.
PMID:3372354
Abstract
A new cytotoxic and antifungal antibiotic, neihumicin, was isolated from the culture broth of a soil isolate identified as Micromonospora neihuensis Wu, sp. nov. Neihumicin shows in vitro cytotoxicity against KB tissue culture cells (ED50 0.94 micrograms/ml) as well as antifungal activity against Saccharomyces cerevisiae ATCC 9763.
摘要
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