Yang L M, Wu R Y, McPhail A T, Yokoi T, Lee K H
Natural Products Laboratory, School of Pharmacy, University of North Carolina, Chapel Hill 27514.
J Antibiot (Tokyo). 1988 Apr;41(4):488-93. doi: 10.7164/antibiotics.41.488.
The structure of neihumicin, a new antibiotic isolated from the fermentation broth of Micromonospora neihuensis Wu, sp. nov., has been determined as (Z)-3,(Z)-6-dibenzylidene-2-methoxy-3,6-dihydropyrazin-5-one based upon spectral evidence and X-ray crystallographic analysis. Its total synthesis has also been achieved.
