State Key Laboratory of Environment Health (Incubation), Key Laboratory of Environment and Health, Ministry of Education, Key Laboratory of Environment and Health (Wuhan), Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, #13 Hangkong Road, Wuhan, 430030, Hubei, China.
Mikrochim Acta. 2021 Mar 15;188(4):126. doi: 10.1007/s00604-021-04779-0.
A fluorescent probe has been developed for tetra bromo bisphenol A (TBBPA) detection based on molecularly imprinted polymers (MIPs) combined with wrinkled silica nanoparticles (WSNs) and CdTe quantum dot (QD) hybrid particles. The WSNs with large pore sizes were employed as a structural support platform for QD embedding, and MIPs were synthesized on the surface of QD-embedded WSNs. The synthetic procedure was characterized using transmission electron microscopy, Brunauer-Emmett-Teller measurements, X-ray photoelectron spectrometry, Fourier transform infrared spectroscopy, and zeta potential analysis. The MIP-capped wrinkled silica-QD hybrid particles (WSNs-QDs-MIPs) possessed an adsorption capacity of 96.5 mg g with an imprinting factor of 7.9 towards TBBPA. Under the optimum incubation conditions, the fluorescence intensity (λ = 340 nm, λ = 605 nm) was quenched in proportion to added TBBPA in the range 0.025 to 5 μM with a limit of detection of 5.4 nM. The developed probe was successfully applied to the detection of TBBPA in plastic electronic waste samples and the results of this method agreed with those obtained using high-performance liquid chromatography. This method presented a satisfactory selectivity, stability, and reproducibility indicating its potential as a promising probe for TBBPA detection.
一种基于分子印迹聚合物（MIPs）与皱状硅纳米粒子（WSNs）和 CdTe 量子点（QD）杂化粒子结合的四溴双酚 A（TBBPA）荧光探针已被开发出来。大孔径的 WSNs 被用作 QD 嵌入的结构支撑平台，并且在嵌入 QD 的 WSNs 表面合成了 MIPs。通过透射电子显微镜、BET 测量、X 射线光电子能谱、傅里叶变换红外光谱和 zeta 电位分析对合成过程进行了表征。MIP 封端的皱状硅-QD 杂化粒子（WSNs-QDs-MIPs）对 TBBPA 的吸附容量为 96.5mg g，印迹因子为 7.9。在最佳孵育条件下，荧光强度（λ=340nm，λ=605nm）在 0.025 至 5μM 的范围内与加入的 TBBPA 呈比例猝灭，检测限为 5.4nM。该探针成功应用于塑料电子废物样品中 TBBPA 的检测，该方法的结果与高效液相色谱法的结果一致。该方法表现出令人满意的选择性、稳定性和重现性，表明其有望成为 TBBPA 检测的一种有前途的探针。
