Eggermont J J, Salamy A
Department of Psychology, University of Calgary, Alberta, Canada.
Hear Res. 1988 Apr;33(1):35-47. doi: 10.1016/0378-5955(88)90019-6.
Since maturation of ABR amplitude and latency in principle are dependent on innate as well as environmental factors and the health of the infant, it is conceivable that prematurely born infants show a maturation profile that is different from that of full term infants. In order to unequivocally address this we analyzed ABRs recorded in 465 full term infants and in 179 healthy prematurely born, of which 65 were tested once and 113 were tested (2-9 occasions) at different ages from birth up to 5 years of age. Our emphasis was on a description in terms of time constants of the exponential functions used to describe the maturational changes. In general one exponential function (time constant about 5 weeks) was needed to describe the changes in full term wave I latency. The sum of two exponentials was required to describe adequately the latency changes for full term wave V (time constants about 5 weeks and 100 weeks). In prematurely born infants all time constants for the wave I and wave V changes were longer than in the full term. For the wave I-wave V interval no difference was found between the two populations. The differences in the time course for wave I and wave V latency can be accounted for by the higher incidence of otitis media in the prematurely born group.
由于听性脑干反应（ABR）波幅和潜伏期的成熟原则上取决于先天因素、环境因素以及婴儿的健康状况，因此可以想象，早产儿的成熟模式与足月儿不同。为了明确解决这一问题，我们分析了465名足月儿和179名健康早产儿的ABR记录，其中65名只接受了一次测试，113名在从出生到5岁的不同年龄段接受了（2至9次）测试。我们重点是根据用于描述成熟变化的指数函数的时间常数进行描述。一般来说，需要一个指数函数（时间常数约为5周）来描述足月儿I波潜伏期的变化。需要两个指数函数的总和才能充分描述足月儿V波潜伏期的变化（时间常数约为5周和100周）。在早产儿中，I波和V波变化的所有时间常数都比足月儿长。对于I波-V波间期，两组之间未发现差异。早产儿组中耳炎发病率较高可以解释I波和V波潜伏期时间进程的差异。
