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与 COVID-19 相关的单侧下垂直视野缺损。

Unilateral inferior altitudinal visual field defect related to COVID-19.

机构信息

Department of Ophthalmology, Goa Medical College, Bambolim, Goa, India.

出版信息

Indian J Ophthalmol. 2021 Apr;69(4):989-991. doi: 10.4103/ijo.IJO_3666_20.

DOI:10.4103/ijo.IJO_3666_20
PMID:33727475
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8012933/
Abstract

Ocular manifestations of COVID-19 are still being studied. Posterior segment involvement in viral entities is either direct viral involvement or a delayed immune response to the antigen. A 22-year-old woman presented with history of perceiving absolute inferior scotoma in the right eye for 4 days and history of fever and sore throat 10 days ago. Fundus examination revealed disc edema and vessel tortuosity. Humphreys Field Analyzer confirmed inferior field defect and Optical Coherence Tomography showed superior, nasal and inferior retinal nerve fiber layer thickening in the right eye. Patient was positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by reverse transcription polymerase chain reaction (RT-PCR) testing. Patient received three doses of injection methylprednisolone over 3 days. There was subjective resolution of scotoma reported 3 weeks posttreatment. We bring forward the first reported case of parainfectious optic neuritis associated with COVID-19.

摘要

COVID-19 的眼部表现仍在研究中。病毒引起的后节疾病既有直接的病毒侵袭,也有针对抗原的延迟免疫反应。一名 22 岁女性,右眼有 4 天的绝对下视野缺损史,10 天前有发热和咽痛史。眼底检查显示视盘水肿和血管迂曲。Humphreys 视野分析仪证实下方视野缺损,光学相干断层扫描显示右眼上方、鼻侧和下方视网膜神经纤维层增厚。逆转录聚合酶链反应(RT-PCR)检测患者 SARS-CoV-2 呈阳性。患者在 3 天内接受了 3 剂注射用甲基强的松龙治疗。治疗后 3 周报告主观视野缺损消失。我们提出首例与 COVID-19 相关的副感染性视神经炎病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56a/8012933/2f58ed4ff98c/IJO-69-989-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56a/8012933/ad0d159f7b10/IJO-69-989-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56a/8012933/48bc6a78be40/IJO-69-989-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56a/8012933/2f58ed4ff98c/IJO-69-989-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56a/8012933/ad0d159f7b10/IJO-69-989-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56a/8012933/48bc6a78be40/IJO-69-989-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56a/8012933/2f58ed4ff98c/IJO-69-989-g003.jpg

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