Hollyer Jennifer A, McGuinness Eamon, Bowers Lisa C, Didier Elizabeth S, Giudice Chiara, Perl Daniel P, Fogarty Ursula
Irish Equine Centre, County Kildare, Ireland.
O'Byrne & Halley, The Laboratory Coolmore Stud, County Tipperary, Ireland.
J Equine Vet Sci. 2014 Nov-Dec;34(11-12):1348-1351. doi: 10.1016/j.jevs.2014.09.002. Epub 2014 Sep 16.
A case of encephalitis of unknown origin in the horse was investigated. Postmortem examination findings revealed a nonsuppurative granulomatous meningoencephalitis in the right hemisphere of the cerebral cortex. Testing for West Nile virus, equine herpes virus, equine infectious anemia, , , and were negative. The horse had a titer for , and sections from the affected area of the brain tested positive for the organism using both polymerase chain reaction (PCR) and immunohistochemistry. Amplicons generated using PCR were sequenced, and genotype II was identified. This is the first case of genotype II associated with encephalitis in the horse.
对一匹患有不明原因脑炎的马进行了调查。尸检结果显示大脑皮层右半球存在非化脓性肉芽肿性脑膜脑炎。对西尼罗河病毒、马疱疹病毒、马传染性贫血等的检测均为阴性。这匹马对[具体物质未给出名称]有滴度，并且使用聚合酶链反应（PCR）和免疫组织化学方法对来自大脑感染区域的切片进行检测，结果显示该生物体呈阳性。对PCR产生的扩增子进行测序，鉴定出为[具体物质未给出名称]基因型II。这是首例与马脑炎相关的[具体物质未给出名称]基因型II病例。
