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一名慢性丙型肝炎病毒感染的吸毒者发生白色念珠菌肺脓肿。

Candida Albicans Lung Abscess in an Illicit Drugs User With Hepatitis C Virus Chronic Infection.

作者信息

Zippi Maddalena, Toma Antonella, Maccioni Francesca, Pica Roberta

机构信息

Unit of Gastroenterology and Digestive Endoscopy, Sandro Pertini Hospital, Rome, ITA.

Unit of Urgent Digestive Endoscopy, Sandro Pertini Hospital, Rome, ITA.

出版信息

Cureus. 2021 Feb 4;13(2):e13117. doi: 10.7759/cureus.13117.

DOI:10.7759/cureus.13117
PMID:33728135
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7935243/
Abstract

Illicit substances are widely used all over the world. Among them, crack cocaine results to be the most used drug for the fact that it can be taken in different ways, such as inhaled or intravenous. Pulmonary complications are well known in people snorting it, mostly due to contamination with other substances contained in the objects able to infuse the drug. Herein, we present a case of lung candida abscess related to nasal insufflation of cocaine in an abuser patient suffering from hepatitis C virus (HCV) and not immunocompromised.

摘要

非法药物在世界各地广泛使用。其中,快克可卡因是使用最广泛的毒品,因为它可以通过不同方式摄入,如吸入或静脉注射。吸食快克可卡因的人肺部并发症众所周知,主要是由于用于注入毒品的物品中所含的其他物质造成的污染。在此,我们报告一例与可卡因鼻吸有关的肺念珠菌脓肿病例,该滥用药物患者患有丙型肝炎病毒(HCV)且无免疫功能低下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/512d/7935243/0641c32eb614/cureus-0013-00000013117-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/512d/7935243/6862b3f6c311/cureus-0013-00000013117-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/512d/7935243/0641c32eb614/cureus-0013-00000013117-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/512d/7935243/6862b3f6c311/cureus-0013-00000013117-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/512d/7935243/0641c32eb614/cureus-0013-00000013117-i02.jpg

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本文引用的文献

1
Effective pharmacotherapy for lung abscess in a patient with alcoholism.酒精中毒患者肺脓肿的有效药物治疗。
Respir Med Case Rep. 2020 Apr 21;30:101061. doi: 10.1016/j.rmcr.2020.101061. eCollection 2020.
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HCV Extrahepatic Manifestations.丙型肝炎病毒的肝外表现
J Clin Transl Hepatol. 2019 Jun 28;7(2):172-182. doi: 10.14218/JCTH.2018.00049. Epub 2019 Apr 21.
3
Candida pneumonia with severe clinical course, recovery with antifungal therapy and unusual pathologic findings: A case report.念珠菌性肺炎伴严重临床病程,经抗真菌治疗后康复及不寻常病理表现:一例报告
Medicine (Baltimore). 2018 Jan;97(2):e9650. doi: 10.1097/MD.0000000000009650.
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Cytosolic phospholipase A2 contributes to innate immune defense against Candida albicans lung infection.胞质型磷脂酶A2有助于机体对白色念珠菌肺部感染的天然免疫防御。
BMC Immunol. 2016 Aug 8;17(1):27. doi: 10.1186/s12865-016-0165-9.
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Crack Cocaine Injection Practices and HIV Risk: Findings From New York and Bridgeport.可卡因注射行为与艾滋病毒风险:来自纽约和布里奇波特的研究结果
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Drug Alcohol Depend. 2006 Feb 28;81(3):221-9. doi: 10.1016/j.drugalcdep.2005.07.011. Epub 2005 Sep 19.
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Respiratory and systemic mycoses: an overview.呼吸道和全身性真菌病:概述
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Pulmonary alterations in cocaine users.可卡因使用者的肺部改变。
Sao Paulo Med J. 2004 Jan 8;122(1):26-31. doi: 10.1590/s1516-31802004000100007.
10
Laboratory diagnosis of lower respiratory tract infections: controversy and conundrums.下呼吸道感染的实验室诊断:争议与难题
J Clin Microbiol. 2002 Sep;40(9):3115-20. doi: 10.1128/JCM.40.9.3115-3120.2002.