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一名接受静脉抗生素治疗慢性莱姆病的患者发生外周静脉穿刺中心静脉导管相关感染性心内膜炎。

Peripherally Inserted Central Catheter-Associated Endocarditis in a Patient Receiving Intravenous Antibiotics for Chronic Lyme Disease.

作者信息

Njie Aji B, Mitchell Michael, Pukkila-Worley Read

机构信息

Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

出版信息

Open Forum Infect Dis. 2021 Mar 5;8(3):ofab041. doi: 10.1093/ofid/ofab041. eCollection 2021 Mar.

DOI:10.1093/ofid/ofab041
PMID:33728358
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7944348/
Abstract

Long-term antibiotics are not effective for the therapy of patients with persistent symptoms and a history of Lyme disease. However, some clinicians still prescribe these therapies. We present a case of peripherally inserted central catheter-associated endocarditis in a patient who had been receiving intravenous antibiotics for the management of chronic Lyme disease. This case highlights an important risk associated with the unscientific use of indwelling peripheral catheters and intravenous antibiotics for the management of such patients.

摘要

长期使用抗生素对有莱姆病病史且症状持续的患者治疗无效。然而，一些临床医生仍会开具这些疗法。我们报告一例接受静脉抗生素治疗慢性莱姆病的患者发生外周静脉穿刺中心静脉导管相关性心内膜炎的病例。该病例凸显了对此类患者不合理使用留置外周导管和静脉抗生素所带来的一项重要风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e2d/7944348/37fe4789dc46/ofab041_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e2d/7944348/eb5512528c69/ofab041_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e2d/7944348/d036688bdfd2/ofab041_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e2d/7944348/37fe4789dc46/ofab041_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e2d/7944348/eb5512528c69/ofab041_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e2d/7944348/d036688bdfd2/ofab041_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e2d/7944348/37fe4789dc46/ofab041_fig3.jpg

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Serious Bacterial Infections Acquired During Treatment of Patients Given a Diagnosis of Chronic Lyme Disease - United States.美国慢性莱姆病患者治疗期间获得的严重细菌感染
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评估莱姆病患者中延长疗程抗生素治疗的发生率和模式。
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High frequency of false positive IgM immunoblots for Borrelia burgdorferi in clinical practice.临床上 Borrelia burgdorferi 的 IgM 免疫印迹出现假阳性的频率很高。
Clin Microbiol Infect. 2012 Dec;18(12):1236-40. doi: 10.1111/j.1469-0691.2011.03749.x. Epub 2012 Feb 28.
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Central venous catheter-associated Nocardia bacteremia in cancer patients.癌症患者中心静脉导管相关诺卡菌血症。
Emerg Infect Dis. 2011 Sep;17(9):1651-8. doi: 10.3201/eid1709.101810.
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Study and treatment of post Lyme disease (STOP-LD): a randomized double masked clinical trial.莱姆病后综合征的研究与治疗（STOP-LD）：一项随机双盲临床试验。
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