Bollow Matthias
Klinik für diagnostische und interventionelle Radiologie, Augusta-Kranken-Anstalt Bochum, Ruhr-Universität Bochum, Bergstraße 26, 44791, Bochum, Deutschland.
Radiologe. 2021 Apr;61(4):351-361. doi: 10.1007/s00117-021-00831-5. Epub 2021 Mar 16.
All rheumatic autoimmune diseases are associated with arthritis of the hands, whereby it is possible to differentiate between typical and atypical arthritis patterns, which are key for diagnosis. Rheumatoid arthritis is commonly associated with synovitis of the hands. While patients with disease duration of less than 2 years were previously considered to have early disease, unfavorable prognosis with delayed initiation of therapy has reduced this time frame to 3 months after symptom onset.
The aim is to provide radiologists with a systematic description of the clinical aspects of rheumatoid arthritis in order to better understand this entity so that they can confidently recognize arthritis patterns in the hands at an early stage.
Narrative review based on the current literature on the subject from radiological and rheumatological point of view.
Synovitis of the hands is a common manifestation in rheumatoid arthritis. Knowledge of the epidemiology, prevalence, incidence, pathogenesis, genetics, etiology, biology and immunology, serology, histology, clinical presentation, the classification and diagnostic criteria, and therapy is essential for the radiologist to better understand the image-based morphologic changes associated with this complex disease and thereby gain greater confidence in the diagnosis of early stages.
For the diagnosis of rheumatoid arthritis, the radiologist must be familiar with basic clinical knowledge to confidently analyze the patterns present in arthritis of the hands at initial diagnosis and during the course of the disease, which are essential for therapy decisions.
所有风湿性自身免疫性疾病均与手部关节炎相关,据此可区分典型和非典型关节炎模式,这是诊断的关键。类风湿关节炎通常与手部滑膜炎相关。以往,疾病病程小于2年的患者被视为早期疾病,但由于治疗延迟会导致不良预后,这一时间框架已缩短至症状出现后3个月。
旨在向放射科医生系统描述类风湿关节炎的临床特征,以便更好地理解这一疾病实体,从而使其能够在早期阶段自信地识别手部的关节炎模式。
基于从放射学和风湿病学角度有关该主题的当前文献进行叙述性综述。
手部滑膜炎是类风湿关节炎的常见表现。了解流行病学、患病率、发病率、发病机制、遗传学、病因、生物学和免疫学、血清学、组织学、临床表现、分类和诊断标准以及治疗方法,对于放射科医生更好地理解与这种复杂疾病相关的基于图像的形态学变化,并从而在早期诊断中获得更大的诊断信心至关重要。
对于类风湿关节炎的诊断,放射科医生必须熟悉基本临床知识,以便在初始诊断和疾病过程中自信地分析手部关节炎中存在的模式,这对于治疗决策至关重要。