• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[手部类风湿关节炎:第一部分:临床方面]

[Rheumatoid arthritis of the hand : Part 1: Clinical aspects].

作者信息

Bollow Matthias

机构信息

Klinik für diagnostische und interventionelle Radiologie, Augusta-Kranken-Anstalt Bochum, Ruhr-Universität Bochum, Bergstraße 26, 44791, Bochum, Deutschland.

出版信息

Radiologe. 2021 Apr;61(4):351-361. doi: 10.1007/s00117-021-00831-5. Epub 2021 Mar 16.

DOI:10.1007/s00117-021-00831-5
PMID:33728481
Abstract

BACKGROUND

All rheumatic autoimmune diseases are associated with arthritis of the hands, whereby it is possible to differentiate between typical and atypical arthritis patterns, which are key for diagnosis. Rheumatoid arthritis is commonly associated with synovitis of the hands. While patients with disease duration of less than 2 years were previously considered to have early disease, unfavorable prognosis with delayed initiation of therapy has reduced this time frame to 3 months after symptom onset.

OBJECTIVE

The aim is to provide radiologists with a systematic description of the clinical aspects of rheumatoid arthritis in order to better understand this entity so that they can confidently recognize arthritis patterns in the hands at an early stage.

MATERIALS AND METHODS

Narrative review based on the current literature on the subject from radiological and rheumatological point of view.

RESULTS

Synovitis of the hands is a common manifestation in rheumatoid arthritis. Knowledge of the epidemiology, prevalence, incidence, pathogenesis, genetics, etiology, biology and immunology, serology, histology, clinical presentation, the classification and diagnostic criteria, and therapy is essential for the radiologist to better understand the image-based morphologic changes associated with this complex disease and thereby gain greater confidence in the diagnosis of early stages.

CONCLUSIONS

For the diagnosis of rheumatoid arthritis, the radiologist must be familiar with basic clinical knowledge to confidently analyze the patterns present in arthritis of the hands at initial diagnosis and during the course of the disease, which are essential for therapy decisions.

摘要

背景

所有风湿性自身免疫性疾病均与手部关节炎相关,据此可区分典型和非典型关节炎模式,这是诊断的关键。类风湿关节炎通常与手部滑膜炎相关。以往,疾病病程小于2年的患者被视为早期疾病,但由于治疗延迟会导致不良预后,这一时间框架已缩短至症状出现后3个月。

目的

旨在向放射科医生系统描述类风湿关节炎的临床特征,以便更好地理解这一疾病实体,从而使其能够在早期阶段自信地识别手部的关节炎模式。

材料与方法

基于从放射学和风湿病学角度有关该主题的当前文献进行叙述性综述。

结果

手部滑膜炎是类风湿关节炎的常见表现。了解流行病学、患病率、发病率、发病机制、遗传学、病因、生物学和免疫学、血清学、组织学、临床表现、分类和诊断标准以及治疗方法,对于放射科医生更好地理解与这种复杂疾病相关的基于图像的形态学变化,并从而在早期诊断中获得更大的诊断信心至关重要。

结论

对于类风湿关节炎的诊断,放射科医生必须熟悉基本临床知识,以便在初始诊断和疾病过程中自信地分析手部关节炎中存在的模式,这对于治疗决策至关重要。

相似文献

1
[Rheumatoid arthritis of the hand : Part 1: Clinical aspects].[手部类风湿关节炎:第一部分:临床方面]
Radiologe. 2021 Apr;61(4):351-361. doi: 10.1007/s00117-021-00831-5. Epub 2021 Mar 16.
2
[Rheumatoid arthritis of the hand : Part 2: Imaging].手部类风湿关节炎:第2部分:影像学
Radiologe. 2021 Apr;61(4):362-374. doi: 10.1007/s00117-021-00833-3. Epub 2021 Mar 16.
3
[Atypical arthritis of the hands : Collagenosis-part 2].[手部非典型关节炎:胶原病 - 第2部分]
Radiologe. 2021 May;61(5):470-482. doi: 10.1007/s00117-021-00842-2. Epub 2021 Apr 1.
4
[Typical arthritis of the hands : Psoriatic arthritis].[手部典型关节炎:银屑病关节炎]
Radiologe. 2021 May;61(5):448-457. doi: 10.1007/s00117-021-00841-3. Epub 2021 Mar 30.
5
[Atypical arthritis of the hands : Collagenosis-part 1].[手部非典型关节炎:胶原病 - 第1部分]
Radiologe. 2021 May;61(5):458-469. doi: 10.1007/s00117-021-00840-4. Epub 2021 Mar 29.
6
Real benefits of ultrasound evaluation of hand and foot synovitis for better characterisation of the disease activity in rheumatoid arthritis.超声评估手足滑膜炎对类风湿关节炎疾病活动更好的特征化的实际获益。
Eur Radiol. 2019 Nov;29(11):6345-6354. doi: 10.1007/s00330-019-06187-8. Epub 2019 Apr 26.
7
Bilateral evaluation of the hand and wrist in untreated early inflammatory arthritis: a comparative study of ultrasonography and magnetic resonance imaging.未经治疗的早期炎症性关节炎患者手部和腕部的双侧评估:超声与磁共振成像的对比研究。
J Rheumatol. 2013 Aug;40(8):1282-92. doi: 10.3899/jrheum.120713. Epub 2013 Jun 1.
8
Magnetic Resonance Imaging of Bilateral Hands Is More Optimal Than MRI of Unilateral Hands for Rheumatoid Arthritis.双手磁共振成像比单侧手磁共振成像更有利于类风湿关节炎。
J Rheumatol. 2018 Jul;45(7):895-904. doi: 10.3899/jrheum.171044. Epub 2018 May 1.
9
Contribution of Ultrasonography of Hands and Wrists in Early Rheumatoid Arthritis.手部和腕部超声在早期类风湿关节炎中的作用。
Curr Rheumatol Rev. 2021;17(3):342-348. doi: 10.2174/1573397117666210219120400.
10
Assessing synovitis in the hands in patients with rheumatoid arthritis by ultrasound: an agreement study exploring the most inflammatory active side from two Norwegian trials.评估类风湿关节炎患者手部的滑膜炎:一项来自两个挪威试验的最具炎症活性侧的一致性研究。
Arthritis Res Ther. 2019 Jul 5;21(1):166. doi: 10.1186/s13075-019-1930-y.

引用本文的文献

1
Investigation of the Role of the TRPA1 Ion Channel in Conveying the Effect of Dimethyl Trisulfide on Vascular and Histological Changes in Serum-Transfer Arthritis.瞬时受体电位锚蛋白1离子通道在传递二甲基三硫化物对血清转移关节炎血管及组织学变化影响中的作用研究
Pharmaceuticals (Basel). 2022 May 27;15(6):671. doi: 10.3390/ph15060671.

本文引用的文献

1
Cytokines as biomarkers in rheumatoid arthritis.细胞因子作为类风湿性关节炎的生物标志物
Mediators Inflamm. 2014;2014:545493. doi: 10.1155/2014/545493. Epub 2014 Mar 9.
2
Rheumatoid Arthritis: Early diagnosis and treatment outcomes.类风湿关节炎:早期诊断与治疗结果
Caspian J Intern Med. 2011 Winter;2(1):161-70.
3
Up-regulation of cytokines and chemokines predates the onset of rheumatoid arthritis.细胞因子和趋化因子的上调早于类风湿性关节炎的发病。
Arthritis Rheum. 2010 Feb;62(2):383-91. doi: 10.1002/art.27186.
4
[Transformation of synovial cells in rheumatoid arthritis (author's transl)].类风湿关节炎中滑膜细胞的转化(作者译)
Verh Dtsch Ges Pathol. 1980;64:193-212.