Pediatric Gastroenterology and Cystic Fibrosis Unit, Department of Human Pathology in Adulthood and Childhood "G. Barresi", University of Messina, Via Consolare Valeria 1, 98124, Messina, Italy.
Division of Digestive Endoscopy, University of Messina, Messina, Italy.
Eur J Pediatr. 2021 Jul;180(7):2281-2286. doi: 10.1007/s00431-021-04017-y. Epub 2021 Mar 16.
The aim of this study was to describe the frequency, major symptoms, and characteristics of colonic polyps in a cohort of children. A retrospective chart review of patients aged ≤ 18 years who were diagnosed with colonic polyp(s) from 2006 to 2019 in a tertiary hospital was included. Data collected included demographics, clinical presentation, interval of time between the onset of symptoms and the endoscopic diagnosis of colonic polyps, family history, characteristics of the polyp, and associated lesions. Over the study period, 35 Caucasian children were diagnosed with juvenile colonic polyps. Twenty-three patients (65.7%) were males. Lower gastrointestinal bleeding of a mean duration of 5.3 ± 4.9 months was the presenting symptom in nearly all cases (n = 34, 97%), and it was isolated in 17 patients. Clinical presentation did not significantly vary according to the age or the location or size of the polyp (p = 0.262, p = 1.000, and p = 0.149, respectively). The polyps were mainly located in the left colon (n = 29, 83%). Right colonic polyps were significantly larger than left colonic polyps (p = 0.037).Conclusion: Lower gastrointestinal bleeding represents the most common presentation of colonic polyps in children. Right-sided colonic polyps occur and may be even larger than left-sided ones. A total colonoscopy is therefore mandatory for all cases of suspected colonic polyps. This study represents a real-life contribution, and it can help improve the management strategies of this condition in childhood. What is Known: • Colonic polyps are quite common in children. • The majority of pediatric colonic polyps are solitary, benign, and located in the left colon. What is New: • Right-sided colonic polyps occur and may be even larger than left-sided ones. • A total colonoscopy is mandatory for all cases of suspected colonic polyps.
本研究旨在描述儿童结肠息肉的发生频率、主要症状和特征。对 2006 年至 2019 年期间在一家三级医院被诊断为结肠息肉的年龄≤18 岁的患者进行回顾性图表审查。收集的数据包括人口统计学特征、临床表现、症状出现与结肠镜诊断结肠息肉之间的时间间隔、家族史、息肉特征和相关病变。在研究期间,35 名白种人儿童被诊断为青少年结肠息肉。23 名患者(65.7%)为男性。下消化道出血平均持续时间为 5.3±4.9 个月,几乎所有患者(n=34,97%)都有这种表现,17 名患者表现为孤立性下消化道出血。临床表现与年龄、息肉位置或大小无关(p=0.262,p=1.000,p=0.149)。息肉主要位于左结肠(n=29,83%)。右结肠息肉明显大于左结肠息肉(p=0.037)。结论:下消化道出血是儿童结肠息肉最常见的表现。右结肠息肉较常见,且可能更大。因此,所有疑似结肠息肉的病例均需进行全结肠镜检查。本研究是一项真实的研究,有助于改善儿童结肠息肉的治疗策略。已知:1. 结肠息肉在儿童中较为常见。2. 大多数儿童结肠息肉为单发、良性,位于左结肠。新发现:1. 右结肠息肉较常见,且可能更大。2. 所有疑似结肠息肉的病例均需进行全结肠镜检查。