Division of Mental Health & Addiction, Vestfold Hospital Trust, Tønsberg, Norway.
Department of Psychology, University of Oslo, Oslo, Norway.
Neurocase. 2021 Apr;27(2):147-154. doi: 10.1080/13554794.2021.1893339. Epub 2021 Mar 17.
The study follows an intellectually superior patient from initial subjective memory complaints to MCI and dementia over 21 years. Primary memory measures, process- and reliable change-measures from 12 assessments with the California Verbal Learning Test (CVLT) were analyzed as well as experimental measures of retrieval and Recency-Ratio (Rr) combining traditional recency measures with selective retrieval impairments of recency items.Recency change preceded normatively impaired memory by four years, and retention percentage by two years. Rr indicated risk for MCI conversion 13 years prior to receiving that diagnosis, and is an interesting measure for early detection of dementia in CVLT.
该研究对一名智力超群的患者进行了长达 21 年的随访，从最初的主观记忆主诉到 MCI 和痴呆。主要记忆测量、12 次加利福尼亚语言学习测试（CVLT）的过程和可靠变化测量以及检索和近期-比率（Rr）的实验测量，近期-比率（Rr）将传统的近期测量与近期项目的选择性检索障碍结合起来进行分析。近期变化比正常记忆障碍提前四年，比保留率提前两年。Rr 表明在接受 MCI 诊断前 13 年就有 MCI 转化的风险，并且是 CVLT 中痴呆早期检测的一个有趣指标。
