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经十二指肠活检偶然诊断。

Diagnosed Incidentally by Duodenal Biopsy.

机构信息

Baystate Medical Center, Springfield, MA, USA.

出版信息

J Investig Med High Impact Case Rep. 2021 Jan-Dec;9:23247096211001649. doi: 10.1177/23247096211001649.

DOI:10.1177/23247096211001649
PMID:33733914
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7983489/
Abstract

(also referred to as and ) is the most common intestinal parasite in the world, affecting approximately 200 million people annually. Symptoms of include foul-smelling diarrhea, abdominal cramping, bloating, gas, and nausea. Although usually self-limiting, can progress to dehydration, malnutrition, and failure to thrive, especially in immunocompromised individuals. Early diagnosis and treatment is imperative to prevent and control infection of . Infectious Disease Society of America diagnostic guidelines recommend obtaining stool studies to diagnose ; when stool studies are negative but suspicion remains high, duodenal aspirate microscopy is the only alternative diagnostic strategy suggested. We report a patient diagnosed incidentally with from a duodenal biopsy specimen obtained during a workup for a gastrointestinal bleed. There are limited cases of diagnosed by duodenal biopsy reported in the literature. We review studies that suggest duodenal biopsy can be a very sensitive strategy for the diagnosis of .

摘要

(也被称为 和 )是世界上最常见的肠道寄生虫,每年影响约 2 亿人。 的症状包括恶臭腹泻、腹部绞痛、腹胀、气胀和恶心。尽管通常是自限性的,但 可能会进展为脱水、营养不良和生长不良,特别是在免疫功能低下的个体中。早期诊断和治疗对于预防和控制 的感染至关重要。美国传染病学会的诊断指南建议进行粪便研究以诊断 ;当粪便研究为阴性但怀疑仍然很高时,十二指肠抽吸显微镜检查是唯一建议的替代诊断策略。我们报告了一例在胃肠道出血检查中偶然通过十二指肠活检诊断 的患者。文献中报道的通过十二指肠活检诊断 的病例有限。我们回顾了一些研究,这些研究表明十二指肠活检可能是诊断 的非常敏感的策略。

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本文引用的文献

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Giardia lamblia infection: review of current diagnostic strategies.蓝氏贾第鞭毛虫感染:当前诊断策略综述
Gastroenterol Hepatol Bed Bench. 2019 Winter;12(1):3-12.
2
Cytopreparation of duodenal biopsy fixative improves detection rate of giardia in clinically suspected cases.十二指肠活检固定剂的细胞制备提高了临床疑似病例中贾第虫的检出率。
Cytopathology. 2019 May;30(3):309-313. doi: 10.1111/cyt.12684. Epub 2019 Apr 1.
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Incidental Diagnosis of Duodenal Giardiasis.十二指肠贾第虫病的偶然诊断
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6
Advances in understanding Giardia: determinants and mechanisms of chronic sequelae.贾第虫研究进展:慢性后遗症的决定因素和机制
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7
Prevalence and risk factors for Giardia duodenalis infection among children: a case study in Portugal.儿童中十二指肠贾第鞭毛虫感染的流行情况和危险因素:葡萄牙的一个病例研究。
Parasit Vectors. 2012 Jan 27;5:22. doi: 10.1186/1756-3305-5-22.
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