Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado, USA,
Rocky Vista University College of Osteopathic Medicine, Parker, Colorado, USA.
Dermatology. 2022;238(1):44-52. doi: 10.1159/000514536. Epub 2021 Mar 18.
The Observational Health Data Sciences and Informatics (OHDSI) network enables access to billions of deidentified, standardized health records and built-in analytics software for observational health research, with numerous potential applications to dermatology. While the use of the OHDSI has increased steadily over the past several years, review of the literature reveals few studies utilizing OHDSI in dermatology. To our knowledge, the University of Colorado School of Medicine is unique in its use of OHDSI for dermatology big data research.
A PubMed search was conducted in August 2020, followed by a literature review, with 24 of the 72 screened articles selected for inclusion. In this review, we discuss the ways OHDSI has been used to compile and analyze data, improve prediction and estimation capabilities, and inform treatment guidelines across specialties. We also discuss the potential for OHDSI in dermatology - specifically, ways that it could reveal adherence to available guidelines, establish standardized protocols, and ensure health equity. Key Messages: OHDSI has demonstrated broad utility in medicine. Adoption of OHDSI by the field of dermatology would facilitate big data research, allow for examination of current prescribing and treatment patterns without clear best practice guidelines, improve the dermatologic knowledge base and, by extension, improve patient outcomes.
观察性健康数据科学和信息学（OHDSI）网络能够访问数十亿份去识别、标准化的健康记录和内置的分析软件，用于观察性健康研究，在皮肤科有许多潜在的应用。尽管 OHDSI 的使用在过去几年中稳步增加，但文献回顾表明，利用 OHDSI 进行皮肤科研究的研究很少。据我们所知，科罗拉多大学医学院是唯一将 OHDSI 用于皮肤科大数据研究的机构。
我们于 2020 年 8 月进行了一次 PubMed 搜索，随后进行了文献综述，从筛选出的 72 篇文章中选择了 24 篇进行纳入。在这篇综述中，我们讨论了 OHDSI 用于编译和分析数据、提高预测和估计能力以及为各专业提供治疗指南的方法。我们还讨论了 OHDSI 在皮肤科的应用潜力——具体来说，它可以揭示对现有指南的遵守情况、建立标准化方案以及确保健康公平的方式。
OHDSI 在医学领域具有广泛的应用。皮肤科领域采用 OHDSI 将促进大数据研究，能够在没有明确最佳实践指南的情况下检查当前的处方和治疗模式，从而改善皮肤科知识库，并最终改善患者的治疗效果。
