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既往存在的痴呆与股骨颈骨折患者较高的死亡率相关。

Preexisting dementia is associated with higher mortality rate in patients with femoral neck fracture.

作者信息

Rajeev Aysha, Ali Mohammed, Tuinebreijer Wim, Zourob Emadeldeen, Anto Joseph

机构信息

Queen Elizabeth Hospital Gateshead Health Foundation NHS Trust Gateshead UK.

Health Education North East Newcastle Upon Tyne UK.

出版信息

Aging Med (Milton). 2021 Jan 4;4(1):12-18. doi: 10.1002/agm2.12142. eCollection 2021 Mar.

Abstract

OBJECTIVE

This study aimed to assess the mortality and the influence of age, Abbreviated Mental Test (AMT) scores, and American Society of Anesthesiologists (ASA) grades on patients with dementia and femoral neck fracture (FNF) at 30 days, 4 months, 1 year, and 2 years after undergoing surgery.

METHODS

Of 1296 patients admitted with FNF, 180 had had prefracture dementia. A retrospective study of these 180 patients was carried out. The patient demographics, including age, sex, presence of diabetes mellitus (DM), lipid profile, AMT score, preoperative comorbidities, ASA grade, and incidence of postoperative delirium, were documented.

RESULTS

A total of 113 patients (62.8%) died postoperatively. The mortality rate was 17.7% (20 patients) at 30 days, 54.9% (62 patients) at 4 months, 77.9% (88 patients) at 1 year, and 87.6% (99 patients) at 2 years. The mortally rate in dementia with FNF was three times higher than that in FNF without dementia and was independent of age, ASA grades, DM, lipid profile, AMT scores, and development of postoperative delirium.

CONCLUSIONS

Dementia should be a principal predictive factor in mortality of FNF and should be a key determinant in all frailty scores.

摘要

目的

本研究旨在评估痴呆合并股骨颈骨折(FNF)患者术后30天、4个月、1年和2年的死亡率,以及年龄、简易精神状态检查表(AMT)评分和美国麻醉医师协会(ASA)分级对其的影响。

方法

在1296例因股骨颈骨折入院的患者中,180例在骨折前已患有痴呆症。对这180例患者进行了一项回顾性研究。记录了患者的人口统计学数据,包括年龄、性别、糖尿病(DM)的存在情况、血脂谱、AMT评分、术前合并症、ASA分级以及术后谵妄的发生率。

结果

共有113例患者(62.8%)术后死亡。30天时死亡率为17.7%(20例患者),4个月时为54.9%(62例患者),1年时为77.9%(88例患者),2年时为87.6%(99例患者)。痴呆合并股骨颈骨折患者的死亡率是无痴呆的股骨颈骨折患者的三倍,且与年龄、ASA分级、糖尿病、血脂谱、AMT评分及术后谵妄的发生无关。

结论

痴呆应是股骨颈骨折死亡率的主要预测因素,且应是所有衰弱评分的关键决定因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4768/7954834/f4927baddcbc/AGM2-4-12-g005.jpg

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