Tajalli Mahroo, Li Tricia, Drucker Aaron M, Qureshi Abrar A, Cho Eunyoung
Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Division of Dermatology, Department of Medicine and Women's College Research Institute, Women's College Hospital, Toronto, Canada.
J Psoriasis Psoriatic Arthritis. 2021 Jan;6(1):45-51. doi: 10.1177/2475530320970531. Epub 2020 Nov 3.
Studies on treatment patterns of psoriasis are valuable to evaluate how efficiently individuals with psoriasis are treated and may facilitate improved outcomes for these patients.
To describe treatment patterns of psoriasis among US women.
In the Nurses' Health Study II (NHS II), a prospective study of female nurses, 2107 women reported to have a diagnosis of psoriasis made by a clinician. We sent them the Psoriasis Screening Tool-2, a validated diagnostic tool for psoriasis, which queries age at diagnosis, treatments, type of psoriasis lesions, body surface area involved, and the provider who made the diagnosis.
A total of 1382 women completed and returned the survey, with 1243 of them validated for having psoriasis. 30% of the patients were diagnosed by non-dermatologists. 79% of the patients reported mild, 17% moderate and 4% severe disease. Psoriasis phenotypes were as follows: plaque 41%, scalp 49%, inverse 27%, nail 22% and palmoplantar 15%. Treatment patterns for mild psoriasis were as follows: only topical treatment 58%, systemic therapy and/or phototherapy 16% and no treatment 26%. Treatment patterns for moderate-to-severe disease were as follows: only topical treatment 42%, systemic therapy and/or phototherapy 47% and no treatment 11%.
The majority of women in NHS II with psoriasis have mild disease. A large proportion of psoriasis patients were diagnosed by non-dermatologists. More than half of people with moderate-to-severe disease received no treatment or only topical medications. A considerable percentage of people with psoriasis reported phenotypes other than chronic plaque psoriasis.
银屑病治疗模式的研究对于评估银屑病患者的治疗效率以及改善这些患者的治疗效果具有重要价值。
描述美国女性银屑病的治疗模式。
在护士健康研究II（NHS II）中，一项针对女性护士的前瞻性研究，2107名女性报告经临床医生诊断患有银屑病。我们向她们发送了银屑病筛查工具-2，这是一种经过验证的银屑病诊断工具，该工具询问了诊断年龄、治疗方法、银屑病皮损类型、受累体表面积以及做出诊断的医生。
共有1382名女性完成并返回了调查问卷，其中1243名被证实患有银屑病。30%的患者由非皮肤科医生诊断。79%的患者报告病情为轻度，17%为中度，4%为重度。银屑病的表型如下：斑块型41%，头皮型49%，反向型27%，甲部型22%，掌跖型15%。轻度银屑病的治疗模式如下：仅局部治疗58%，系统治疗和/或光疗16%，未治疗26%。中重度疾病的治疗模式如下：仅局部治疗42%，系统治疗和/或光疗47%，未治疗11%。
NHS II中大多数患有银屑病的女性病情为轻度。很大一部分银屑病患者由非皮肤科医生诊断。超过一半的中重度疾病患者未接受治疗或仅使用局部药物。相当比例的银屑病患者报告的表型不是慢性斑块状银屑病。
