• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Accelerating Metabolite Identification in Natural Product Research: Toward an Ideal Combination of Liquid Chromatography-High-Resolution Tandem Mass Spectrometry and NMR Profiling, in Silico Databases, and Chemometrics.

作者信息

Wolfender Jean-Luc, Nuzillard Jean-Marc, van der Hooft Justin J J, Renault Jean-Hugues, Bertrand Samuel

机构信息

School of Pharmaceutical Sciences, EPGL , University of Geneva, University of Lausanne , CMU, 1 Rue Michel Servet , 1211 Geneva 4, Switzerland.

Institut de Chimie Moléculaire de Reims, UMR CNRS 7312 , Université de Reims Champagne Ardenne , 51687 Reims Cedex 2, France.

出版信息

Anal Chem. 2019 Jan 2;91(1):704-742. doi: 10.1021/acs.analchem.8b05112. Epub 2018 Dec 14.

DOI:10.1021/acs.analchem.8b05112
PMID:30453740
Abstract
摘要

相似文献

1
Accelerating Metabolite Identification in Natural Product Research: Toward an Ideal Combination of Liquid Chromatography-High-Resolution Tandem Mass Spectrometry and NMR Profiling, in Silico Databases, and Chemometrics.加速天然产物研究中的代谢物鉴定：迈向液相色谱-高分辨率串联质谱与核磁共振谱分析、计算机数据库及化学计量学的理想结合
Anal Chem. 2019 Jan 2;91(1):704-742. doi: 10.1021/acs.analchem.8b05112. Epub 2018 Dec 14.
2
UHPLC-QTOF-MS/MS-SPE-NMR: A Solution to the Metabolomics Grand Challenge of Higher-Throughput, Confident Metabolite Identifications.超高效液相色谱-四极杆飞行时间串联质谱-固相萃取-核磁共振联用技术：应对高通量、可靠代谢物鉴定这一代谢组学重大挑战的解决方案。
Methods Mol Biol. 2019;2037:113-133. doi: 10.1007/978-1-4939-9690-2_7.
3
The combination of four analytical methods to explore skeletal muscle metabolomics: Better coverage of metabolic pathways or a marketing argument?四种分析方法联合用于探索骨骼肌代谢组学：是更好地覆盖代谢途径，还是一个营销论点？
J Pharm Biomed Anal. 2018 Jan 30;148:273-279. doi: 10.1016/j.jpba.2017.10.013. Epub 2017 Oct 18.
4
Metabolomics and dereplication strategies in natural products.天然产物中的代谢组学与去重复策略
Methods Mol Biol. 2013;1055:227-44. doi: 10.1007/978-1-62703-577-4_17.
5
Overview of Tandem Mass Spectral and Metabolite Databases for Metabolite Identification in Metabolomics.串联质谱和代谢物数据库概述，用于代谢组学中的代谢物鉴定。
Methods Mol Biol. 2020;2104:139-148. doi: 10.1007/978-1-0716-0239-3_8.
6
Annotation of the human serum metabolome by coupling three liquid chromatography methods to high-resolution mass spectrometry.通过将三种液相色谱方法与高分辨率质谱联用对人血清代谢组进行注释。
J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Sep 1;966:34-47. doi: 10.1016/j.jchromb.2014.04.025. Epub 2014 Apr 21.
7
Plasma metabolome analysis by integrated ionization rapid-resolution liquid chromatography/tandem mass spectrometry.整合离子化快速分辨液相色谱/串联质谱法进行血浆代谢组分析。
Rapid Commun Mass Spectrom. 2013 Sep 30;27(18):2071-80. doi: 10.1002/rcm.6666.
8
Statistically correlating NMR spectra and LC-MS data to facilitate the identification of individual metabolites in metabolomics mixtures.对 NMR 谱和 LC-MS 数据进行统计学关联，以促进代谢组学混合物中单个代谢物的鉴定。
Anal Bioanal Chem. 2019 Mar;411(7):1301-1309. doi: 10.1007/s00216-019-01600-z. Epub 2019 Feb 21.
9
Beyond the paradigm: Combining mass spectrometry and nuclear magnetic resonance for metabolomics.超越范式：质谱与核磁共振联用的代谢组学研究
Prog Nucl Magn Reson Spectrosc. 2017 May;100:1-16. doi: 10.1016/j.pnmrs.2017.01.001. Epub 2017 Jan 11.
10
NMR Spectroscopy-Based Metabolic Profiling of Biospecimens.基于核磁共振光谱法的生物样本代谢谱分析
Curr Protoc Protein Sci. 2019 Dec;98(1):e98. doi: 10.1002/cpps.98.

引用本文的文献

1
Knowledge and data-driven two-layer networking for accurate metabolite annotation in untargeted metabolomics.用于非靶向代谢组学中准确代谢物注释的知识和数据驱动的双层网络
Nat Commun. 2025 Aug 30;16(1):8118. doi: 10.1038/s41467-025-63536-6.
2
Long-Term System Suitability Evaluation for Mass Accuracy in the Analysis of Small Molecules by High-Resolution Mass Spectrometry.高分辨率质谱法分析小分子时质量准确度的长期系统适用性评估
J Am Soc Mass Spectrom. 2025 Sep 3;36(9):2005-2012. doi: 10.1021/jasms.5c00128. Epub 2025 Aug 12.
3
LC-HRMS Coupling to Feature-Based Molecular Networking to Efficiently Annotate Monoterpene Indole Alkaloids of .
液相色谱-高分辨质谱联用与基于特征的分子网络相结合以高效注释……的单萜吲哚生物碱
Plants (Basel). 2025 Jul 14;14(14):2177. doi: 10.3390/plants14142177.
4
Multiparametric Optimization of Data-Dependent Acquisition Towards More Holistic Bacterial Metabolite Coverage Through Molecular Networking.通过分子网络对数据依赖采集进行多参数优化以实现更全面的细菌代谢物覆盖
Int J Microbiol. 2025 Jul 21;2025:4388417. doi: 10.1155/ijm/4388417. eCollection 2025.
5
Multilaboratory Untargeted Mass Spectrometry Metabolomics Collaboration to Identify Bottlenecks and Comprehensively Annotate A Single Dataset.多实验室非靶向质谱代谢组学协作以识别瓶颈并全面注释单个数据集
Anal Chem. 2025 Aug 5;97(30):16110-16122. doi: 10.1021/acs.analchem.4c05577. Epub 2025 Jul 22.
6
Integrating NMR and MS for Improved Metabolomic Analysis: From Methodologies to Applications.整合核磁共振与质谱技术以改进代谢组学分析：从方法到应用
Molecules. 2025 Jun 17;30(12):2624. doi: 10.3390/molecules30122624.
7
Bridging Ethnobotanical Knowledge and Multi-Omics Approaches for Plant-Derived Natural Product Discovery.架起民族植物学知识与多组学方法之间的桥梁以发现植物源天然产物
Metabolites. 2025 May 29;15(6):362. doi: 10.3390/metabo15060362.
8
High-resolution accurate mass- mass spectrometry based- untargeted metabolomics: Reproducibility and detection power across data-dependent acquisition, data-independent acquisition, and AcquireX.基于高分辨率精确质量-质谱的非靶向代谢组学：数据依赖型采集、数据独立型采集和AcquireX之间的重现性与检测能力
Comput Struct Biotechnol J. 2025 May 30;27:2412-2423. doi: 10.1016/j.csbj.2025.05.046. eCollection 2025.
9
Unlocking the Potential of Water-Insoluble Natural Polymers: Isolation, Characterization, and 2D NMR Quantification of -1,4-Poly-β-myrcene in Chios Mastic Gum.挖掘水不溶性天然聚合物的潜力：乳香中-1,4-聚-β-月桂烯的分离、表征及二维核磁共振定量分析
J Nat Prod. 2025 Aug 22;88(8):1879-1886. doi: 10.1021/acs.jnatprod.5c00256. Epub 2025 Apr 14.
10
Traditional Chinese medicine as a promising choice for future control of PEDV.传统中医作为未来控制猪流行性腹泻病毒的一个有前景的选择。
Virus Res. 2025 Jun;356:199572. doi: 10.1016/j.virusres.2025.199572. Epub 2025 Apr 10.