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Micro-organic basis of functional gastrointestinal (GI) disorders: Role of microRNAs in GI pacemaking cells.

作者信息

Singh Rajan, Wei Lai, Ghoshal Uday C

机构信息

Department of Physiology and Cell Biology, University of Nevada, Reno, School of Medicine, Reno, NV, 89557, USA.

Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226 014, India.

出版信息

Indian J Gastroenterol. 2021 Apr;40(2):102-110. doi: 10.1007/s12664-021-01159-7.

DOI:10.1007/s12664-021-01159-7
PMID:33738768
Abstract
摘要

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Inhibition of miRNA-29a regulates intestinal barrier function in diarrhea-predominant irritable bowel syndrome by upregulating ZO-1 and CLDN1.抑制miRNA-29a通过上调紧密连接蛋白1(ZO-1)和闭合蛋白1(CLDN1)来调节腹泻型肠易激综合征的肠道屏障功能。
Exp Ther Med. 2020 Dec;20(6):155. doi: 10.3892/etm.2020.9284. Epub 2020 Oct 6.
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Irritable bowel syndrome.
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Dig Dis Sci. 2023 Jan;68(1):38-53. doi: 10.1007/s10620-022-07516-6. Epub 2022 May 4.
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Front Pharmacol. 2022 Jan 25;13:808195. doi: 10.3389/fphar.2022.808195. eCollection 2022.
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