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孤立亮氨酸和支链氨基酸补充剂对增强肌肉力量和肥大的作用:叙述性综述。

Isolated Leucine and Branched-Chain Amino Acid Supplementation for Enhancing Muscular Strength and Hypertrophy: A Narrative Review.

机构信息

CUNY Lehman College.

Institute of Performance Nutrition.

出版信息

Int J Sport Nutr Exerc Metab. 2021 May 1;31(3):292-301. doi: 10.1123/ijsnem.2020-0356. Epub 2021 Mar 18.

DOI:10.1123/ijsnem.2020-0356
PMID:33741748
Abstract

Branched-chain amino acids (BCAA) are one of the most popular sports supplements, marketed under the premise that they enhance muscular adaptations. Despite their prevalent consumption among athletes and the general public, the efficacy of BCAA has been an ongoing source of controversy in the sports nutrition field. Early support for BCAA supplementation was derived from extrapolation of mechanistic data on their role in muscle protein metabolism. Of the three BCAA, leucine has received the most attention because of its ability to stimulate the initial acute anabolic response. However, a substantial body of both acute and longitudinal research has now accumulated on the topic, affording the ability to scrutinize the effects of BCAA and leucine from a practical standpoint. This article aims to critically review the current literature and draw evidence-based conclusions about the putative benefits of BCAA or leucine supplementation on muscle strength and hypertrophy as well as illuminate gaps in the literature that warrant future study.

摘要

支链氨基酸(BCAA)是最受欢迎的运动补剂之一,其销售的前提是它们能促进肌肉适应。尽管运动员和普通公众普遍消费 BCAA,但它的功效一直是运动营养领域争议的焦点。早期对 BCAA 补充的支持来自于对其在肌肉蛋白质代谢中作用的机制数据的推断。在这三种 BCAA 中,亮氨酸因其能够刺激初始急性合成代谢反应而受到最多关注。然而,现在已经积累了大量关于该主题的急性和纵向研究,使我们能够从实际角度仔细研究 BCAA 和亮氨酸的影响。本文旨在批判性地回顾当前的文献,并从实证的角度得出关于 BCAA 或亮氨酸补充对肌肉力量和肥大的潜在益处的结论,并阐明文献中的空白,这些空白需要进一步研究。

相似文献

1
Isolated Leucine and Branched-Chain Amino Acid Supplementation for Enhancing Muscular Strength and Hypertrophy: A Narrative Review.孤立亮氨酸和支链氨基酸补充剂对增强肌肉力量和肥大的作用:叙述性综述。
Int J Sport Nutr Exerc Metab. 2021 May 1;31(3):292-301. doi: 10.1123/ijsnem.2020-0356. Epub 2021 Mar 18.
2
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Post-exercise branched chain amino acid supplementation does not affect recovery markers following three consecutive high intensity resistance training bouts compared to carbohydrate supplementation.与补充碳水化合物相比,连续进行三次高强度抗阻训练后补充支链氨基酸对恢复指标没有影响。
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Activation of mTORC1 by leucine is potentiated by branched-chain amino acids and even more so by essential amino acids following resistance exercise.亮氨酸激活 mTORC1 的作用可被支链氨基酸增强,在抗阻运动后,这种作用可被必需氨基酸进一步增强。
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Muscle protein anabolism in type 2 diabetes.2 型糖尿病中的肌肉蛋白质合成代谢。
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Eur J Clin Nutr. 2017 May;71(5):587-593. doi: 10.1038/ejcn.2016.161. Epub 2016 Sep 28.

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