Department of Surgery, Unit of General Surgery, University Hospital of Ferrara, University of Ferrara, Ferrara, Italy.
Dipartimento di Morfologia, Chirurgia e Medicina Sperimentale, Università di Ferrara, Ferrara, Italia.
Eur J Trauma Emerg Surg. 2022 Apr;48(2):1205-1216. doi: 10.1007/s00068-021-01646-8. Epub 2021 Mar 19.
The primary aim of this study was to evaluate the 30-day survival of nonagenarian patients who underwent non-traumatic emergency abdominal surgery. Other aims were: 90-day and 12-month survival rates, the postoperative complications rate, the impact of the emergency operation on postoperative functional status, the accuracy of the P-POSSUM in predicting 30-day postoperative mortality and changes in care services after surgery.
This was a retrospective cohort study of nonagenarian patients who underwent non-traumatic emergency abdominal surgery between January 2010 and June 2017. Patients were divided in two groups according to the 30-day survival status to compare the distribution of patients' characteristics and postoperative outcomes. Overall survival was estimated using the Kaplan-Meier method. To assess the accuracy of P-POSSUM to predict 30-day mortality, a receiver operating characteristic curve and the Hosmer-Lemeshow goodness of fit test were used.
85 nonagenarian patients were enrolled in this study; of these, 27 (31.8%) died within 30 days. The Kaplan-Meier curve showed a rapid decline in survival over the first 30 postoperative days, followed by a more gradual reduction during the rest of the first year. The majority of patients (92.6%) who died within 30 days experienced a medical complication, with a preponderance of respiratory failure (48.2%) and multiple organ failure (33.3%). In the surviving patients, the postoperative functional status had worsened, and 64.2% of patients did not return to their original housing situation or were institutionalized. The accuracy of P-POSSUM in predicting 30-day mortality in nonagenarian patients was poor.
This study may help doctors convey the postoperative risks of morbidity and mortality, and also to adequately inform relatives about the possible adverse discharge destination of surviving nonagenarian patients with a consequent increase in care needs.
本研究的主要目的是评估行非创伤性急诊腹部手术的 90 岁以上患者的 30 天生存率。其他目的包括:90 天和 12 个月的生存率、术后并发症发生率、急诊手术对术后功能状态的影响、P-POSSUM 预测 30 天术后死亡率的准确性以及术后护理服务的变化。
这是一项回顾性队列研究,纳入了 2010 年 1 月至 2017 年 6 月间行非创伤性急诊腹部手术的 90 岁以上患者。根据 30 天生存状况将患者分为两组,比较患者特征和术后结局的分布。采用 Kaplan-Meier 法估计总生存率。为评估 P-POSSUM 预测 30 天死亡率的准确性,采用受试者工作特征曲线和 Hosmer-Lemeshow 拟合优度检验。
本研究纳入了 85 名 90 岁以上患者;其中 27 名(31.8%)患者在 30 天内死亡。Kaplan-Meier 曲线显示,术后 30 天内死亡率迅速下降,随后在第一年的剩余时间内逐渐下降。在 30 天内死亡的大多数患者(92.6%)经历了医疗并发症,以呼吸衰竭(48.2%)和多器官衰竭(33.3%)为主。在存活患者中,术后功能状态恶化,64.2%的患者无法返回原来的居住环境或被收容入院。P-POSSUM 预测 90 岁以上患者 30 天死亡率的准确性较差。
本研究可能有助于医生传达发病率和死亡率的术后风险,并充分告知亲属存活的 90 岁以上患者可能出现的不利出院去向,从而增加护理需求。