Dermatology Program, Boston Children's Hospital, Boston, MA, USA.
Harvard Medical School, Boston, MA, USA.
Pediatr Dermatol. 2021 May;38(3):712-713. doi: 10.1111/pde.14585. Epub 2021 Mar 19.
Primary cutaneous anaplastic large cell lymphoma (PC-ALCL) is a CD30+ lymphoproliferative disorder that rarely occurs in children. Although there are currently no consensus guidelines for the treatment of cutaneous lymphoma in the pediatric population, the isolated form of PC-ALCL is typically managed by surgical excision or external beam radiation therapy. We report the case of a 6-year-old girl with primary cutaneous anaplastic large cell lymphoma that was treated with brachytherapy with no recurrence after 21 months of follow-up, suggesting that brachytherapy may be considered as a treatment for pediatric cutaneous large cell anaplastic lymphoma.
原发性皮肤间变大细胞淋巴瘤（PC-ALCL）是一种 CD30+的淋巴增生性疾病，在儿童中很少见。虽然目前针对儿科人群的皮肤淋巴瘤治疗尚无共识指南，但孤立性 PC-ALCL 通常通过手术切除或外照射治疗来管理。我们报告了一例 6 岁女孩患有原发性皮肤间变大细胞淋巴瘤，采用近距离放射治疗，21 个月随访后无复发，表明近距离放射治疗可被视为治疗儿童皮肤间变大细胞淋巴瘤的一种选择。
