Department of Reproductive Biology, UMARE Reproduction Clinic, Mexico City, Mexico.
Department of Infectious Diseases, National Institute of Respiratory Diseases (INER), Mexico City, Mexico.
Am J Case Rep. 2021 Mar 20;22:e929489. doi: 10.12659/AJCR.929489.
BACKGROUND The damage caused by the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) has been extensive. Pregnant women are a group requiring special attention in medicine given the anatomical and physiological changes that occur during pregnancy. Skin rash is commonly associated with pregnancy, with the most common form of an erythematous maculopapular rash being pruritic urticarial papules and plaques of pregnancy. Skin rash is also an increasingly reported initial presentation in patients with coronavirus disease 2019 (COVID-19), due to infection with SARS-CoV-2. CASE REPORT A 34-year-old woman with a diamniotic dichorionic twin pregnancy presented with clinical picture characterized by dermatological manifestations, namely an erythematous and papular skin rash associated with SARS-CoV-2 infection. A real-time reverse transcription-polymerase chain reaction (GeneFinder) test was positive for SARS-CoV-2 detection. CONCLUSIONS Ten months after the onset of this pandemic, there is no conclusive evidence indicating that pregnant women represent a sector more or less vulnerable to severe forms of COVID-19 than the general population. This report has highlighted the importance of performing a reliable diagnostic test for SARS-CoV-2 infection in patients who present with a skin rash, particularly pregnant women.
严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)造成的损害广泛存在。鉴于妊娠期间发生的解剖和生理变化,孕妇是医学上需要特别关注的群体。皮疹常与妊娠有关,最常见的形式是妊娠性红斑性多形性皮疹,即瘙痒性荨麻疹性丘疹和斑块。由于感染了 SARS-CoV-2,皮疹也是 COVID-19 患者越来越多的初始表现。
一位 34 岁的妇女怀有单卵双胎妊娠,表现出具有皮肤表现的临床特征,即伴有 SARS-CoV-2 感染的红斑和丘疹性皮疹。实时逆转录-聚合酶链反应(GeneFinder)检测对 SARS-CoV-2 的检测呈阳性。
在这种大流行发生十个月后,尚无确凿证据表明孕妇比一般人群更容易出现 COVID-19 的严重形式。本报告强调了对出现皮疹的患者(特别是孕妇)进行 SARS-CoV-2 感染可靠诊断测试的重要性。