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机器人辅助与传统腹腔镜手术治疗直肠癌患者的疗效比较:单中心 300 例观察性研究。

Outcomes of robotic-assisted vs conventional laparoscopic surgery among patients undergoing resection for rectal cancer: an observational single hospital study of 300 cases.

机构信息

University of Malaga, Avenida Carlos Haya s/n, Malaga, Spain.

University of Granada, Granada, Spain.

出版信息

J Robot Surg. 2022 Feb;16(1):179-187. doi: 10.1007/s11701-021-01227-2. Epub 2021 Mar 20.

DOI:10.1007/s11701-021-01227-2
PMID:33743145
Abstract

Robotic-assisted laparoscopic surgery attempts to facilitate rectal surgery in the narrow space of the pelvis. The aim of this study is to compare the outcomes of robotic versus laparoscopic surgery for rectal cancer. Monocentric retrospective study including 300 patients who underwent robotic (n = 178) or laparoscopic (n = 122) resection between Jan 2009 and Dec 2017 for high, mid and low rectal cancer. The robotic and laparoscopic groups were comparable with regard to pretreatment characteristics, except for sex and ASA status. There were no statistical differences between groups in the conversion rate to open surgery. Surgical morbidity and oncological quality did not differ in either group, except for the anastomosis leakage rate and the affected distal resection margin. There were no differences in overall survival rate between the laparoscopic and robotic group. Robotic surgery could provide some advantages over conventional laparoscopic surgery, such as three-dimensional views, articulated instruments, lower fatigue, lower conversion rate to open surgery, shorter hospital stays and lower urinary and sexual dysfunctions. On the other hand, robotic surgery usually implies longer operation times and higher costs. As shown in the ROLARR trial, no statistical differences in conversion rate were found between the groups in our study. When performed by experienced surgeons, robotic surgery for rectal cancer could be a safe and feasible option with no significant differences in terms of oncological outcomes in comparison to laparoscopic surgery.

摘要

机器人辅助腹腔镜手术试图在骨盆的狭窄空间中方便直肠手术。本研究的目的是比较机器人与腹腔镜手术治疗直肠癌的结果。这是一项单中心回顾性研究,纳入了 2009 年 1 月至 2017 年 12 月期间接受机器人(n = 178)或腹腔镜(n = 122)直肠切除术的 300 例患者,这些患者的肿瘤位于高位、中位和低位直肠。机器人组和腹腔镜组在术前特征方面具有可比性,除了性别和 ASA 状态。两组中转开腹手术的发生率无统计学差异。两组的手术发病率和肿瘤学质量无差异,除了吻合口漏率和受影响的远端切缘。两组的总生存率无差异。机器人手术相对于传统腹腔镜手术可能具有一些优势,例如三维视图、铰接器械、更低的疲劳度、更低的中转开腹手术率、更短的住院时间以及更低的尿和性功能障碍发生率。另一方面,机器人手术通常意味着手术时间更长,成本更高。正如 ROLARR 试验所示,我们的研究中两组的中转率没有统计学差异。当由经验丰富的外科医生进行操作时,机器人手术治疗直肠癌是一种安全可行的选择,与腹腔镜手术相比,在肿瘤学结果方面没有显著差异。

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本文引用的文献

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A Randomized Trial of Laparoscopic versus Open Surgery for Rectal Cancer.腹腔镜手术与开腹手术治疗直肠癌的随机试验
N Engl J Med. 2015 Jul 9;373(2):194. doi: 10.1056/NEJMc1505367.
肠系膜下动脉的节段、长度、分支类型及与左结肠动脉、肠系膜下静脉的位置关系研究。
BMC Med Imaging. 2022 Mar 8;22(1):38. doi: 10.1186/s12880-022-00764-y.