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J Med Virol. 2021 Oct;93(10):6050-6053. doi: 10.1002/jmv.27162. Epub 2021 Jul 6.

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SARS-CoV-2 has been circulating in northeastern Brazil since February 2020: evidence for antibody detection in asymptomatic patients.自2020年2月以来，严重急性呼吸综合征冠状病毒2（SARS-CoV-2）一直在巴西东北部传播：无症状患者抗体检测的证据。
J Infect. 2021 May;82(5):186-230. doi: 10.1016/j.jinf.2020.11.037. Epub 2020 Dec 1.
2
Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy.在意大利大流行前时期意外检测到 SARS-CoV-2 抗体。
Tumori. 2021 Oct;107(5):446-451. doi: 10.1177/0300891620974755. Epub 2020 Nov 11.
3
Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison.五种 SARS-CoV-2 免疫测定法的性能特征：头对头基准比较。
Lancet Infect Dis. 2020 Dec;20(12):1390-1400. doi: 10.1016/S1473-3099(20)30634-4. Epub 2020 Sep 23.
4
Diagnostic accuracy of serological tests for covid-19: systematic review and meta-analysis.血清学检测在 COVID-19 诊断中的准确性：系统评价和荟萃分析。
BMJ. 2020 Jul 1;370:m2516. doi: 10.1136/bmj.m2516.
5
Assay Techniques and Test Development for COVID-19 Diagnosis.用于新冠病毒诊断的检测技术与测试开发
ACS Cent Sci. 2020 May 27;6(5):591-605. doi: 10.1021/acscentsci.0c00501. Epub 2020 Apr 30.
6
The spectrum effect in tests for risk prediction, screening, and diagnosis.风险预测、筛查和诊断测试中的谱效应。
BMJ. 2016 Jun 22;353:i3139. doi: 10.1136/bmj.i3139.

回顾性低流行时期抗 SARS-CoV-2 免疫球蛋白血清学监测：一个警示故事。

Retrospective serosurveillance for anti-SARS-CoV-2 immunoglobulin during a time of low prevalence: A cautionary tale.

机构信息

Clinical Microbiology, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, LE1 5WW Leicester, United Kingdom.

Clinical Microbiology, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, LE1 5WW Leicester, United Kingdom; Respiratory Sciences, University of Leicester, LE1 9HN, United Kingdom.

出版信息

J Infect. 2021 Jul;83(1):119-145. doi: 10.1016/j.jinf.2021.03.007. Epub 2021 Mar 17.

DOI:10.1016/j.jinf.2021.03.007
PMID:33744303
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7968146/
Abstract

We performed a retrospective screening of 428 serum samples for anti-SARS-CoV-2  immunoglobulin during a period of low prevalence. Employing two different serological tests yielded discrepant results for 10 samples; highlighting an increased risk of potential  false positive results and the need for further confirmatory testing before publication of data.

摘要

我们在低流行期间对 428 份血清样本进行了抗 SARS-CoV-2 免疫球蛋白的回顾性筛查。使用两种不同的血清学检测方法对 10 份样本的检测结果不一致；这突出表明存在潜在假阳性结果的风险增加，并且在发布数据之前需要进一步进行确认性检测。