抗生素对人体肠道中胆固醇向粪甾烷醇微生物转化的影响。

Influence of antibiotics on microbial intestinal transformation of cholesterol to coprostanol in man.

作者信息

Midtvedt T, Frederichsen P

出版信息

Scand J Gastroenterol. 1977;12(6):669-72. doi: 10.3109/00365527709181701.

Abstract

Fecal excretion of coprostanol was followed in groups of healthy volunteers receiving various antibiotics per os. No effect upon excretion was found in the groups receiving phenoximethylpenicillin or doxicycline, whereas a prolonged reduction was found in the groups receiving clindamycin, ampicillin, oxitetracycline or a fixed combination of bacitracin and neomycin.

摘要

对口服各种抗生素的健康志愿者组的粪中粪甾烷醇排泄情况进行了跟踪观察。接受苯氧甲基青霉素或多西环素的组未发现排泄有变化，而接受克林霉素、氨苄青霉素、土霉素或杆菌肽与新霉素固定组合的组则发现排泄有长期减少。