Hussain Humaira, Wattoo Feroza Hamid, Wattoo Muhammad Hamid Sarwar, Gulfraz Muhammad, Masud Tariq, Shah Imam, Ali Sakhawat, Alavi Seyed Ebrahim
University Institute of Biochemistry and Biotechnology PMAS - Arid Agriculture University Rawalpindi Pakistan.
Department of Chemistry Pakistan Institute of Engineering and Applied Sciences Islamabad Pakistan.
Food Sci Nutr. 2021 Feb 2;9(3):1347-1356. doi: 10.1002/fsn3.2078. eCollection 2021 Mar.
Camel milk is a valuable source of nutrition with a wide range of therapeutic effects. Its unique composition helps to regulate the blood glucose level. The current study is aimed to evaluate the antidiabetic and hepatoprotective effects, as well as lipid profile restoration of camel milk in the diabetic mouse model. This innovative study evaluates the therapeutic effects of camel milk in diabetic mice by simultaneous measurement of blood glucose, HbA1c, ALT, AST, TG, cholesterol, and histopathological studies. The results showed that camel milk has significantly reduced blood glucose, HbA1c ( < .001), aspartate transaminase (AST), alanine transaminase (ALT) ( < .01), triglyceride (TG), and cholesterol ( < .01), compared to that in the diabetic control group. Also, the therapeutic effects of camel milk were completely comparable with the antidiabetic drug glibenclamide. The results of this study suggest that camel milk could be used as a proper alternative treatment regimen for diabetes therapy.
骆驼奶是一种具有广泛治疗作用的宝贵营养来源。其独特的成分有助于调节血糖水平。当前的研究旨在评估骆驼奶在糖尿病小鼠模型中的抗糖尿病和肝脏保护作用以及脂质谱恢复情况。这项创新性研究通过同时测量血糖、糖化血红蛋白(HbA1c)、谷丙转氨酶(ALT)、谷草转氨酶(AST)、甘油三酯(TG)、胆固醇以及进行组织病理学研究,来评估骆驼奶对糖尿病小鼠的治疗效果。结果显示,与糖尿病对照组相比,骆驼奶显著降低了血糖、糖化血红蛋白(<0.001)、天冬氨酸转氨酶(AST)、丙氨酸转氨酶(ALT)(<0.01)、甘油三酯(TG)和胆固醇(<0.01)。此外,骆驼奶的治疗效果与抗糖尿病药物格列本脲完全相当。这项研究的结果表明,骆驼奶可作为糖尿病治疗的一种合适替代治疗方案。