利什曼病综述：当前认知与未来方向
A Review of Leishmaniasis: Current Knowledge and Future Directions.
作者信息
Mann Sarah, Frasca Katherine, Scherrer Sara, Henao-Martínez Andrés F, Newman Sabrina, Ramanan Poornima, Suarez José A
机构信息
Division of Infectious Diseases, Department of Internal Medicine, University of Colorado-AMC, 12700 E. 19th Ave., B168, Aurora, CO 80045 USA.
Division of Dermatology, University of Colorado-AMC, Aurora, CO USA.
出版信息
Curr Trop Med Rep. 2021;8(2):121-132. doi: 10.1007/s40475-021-00232-7. Epub 2021 Mar 17.
PURPOSE OF REVIEW
The goal of this review is to summarize the current knowledge of the epidemiology, clinical manifestations, diagnosis, and treatment of cutaneous, mucosal, and visceral leishmaniasis. We will describe the most recent findings and suggest areas of further research in the leishmaniasis field.
RECENT FINDINGS
This article reviews newer leishmaniasis tests (including rapid diagnostic tests using rK39 antibodies), vaccine candidates, and updated treatment recommendations.
SUMMARY
While leishmaniasis is a complex disease, learning the prominent clinical manifestations and major parasite species can guide the recommendations for diagnosis and treatment.
综述目的
本综述的目的是总结皮肤型、黏膜型和内脏型利什曼病在流行病学、临床表现、诊断和治疗方面的现有知识。我们将描述最新研究结果，并提出利什曼病领域进一步研究的方向。
最新发现
本文综述了利什曼病的新型检测方法（包括使用rK39抗体的快速诊断检测）、候选疫苗以及更新的治疗建议。
总结
虽然利什曼病是一种复杂的疾病，但了解其突出的临床表现和主要寄生虫种类可指导诊断和治疗建议。
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